Results 91 to 100 of about 360,376 (378)

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]

open access: yes, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core   +2 more sources

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan   +11 more
wiley   +1 more source

Reflexões sobre a articulação entre o homo faber e o homo sapiens na enfermagem

open access: yesEscola Anna Nery, 2013
Estudo reflexivo com o objetivo de analisar a articulação entre o enfermeiro-docente (Homo sapiens) e o enfermeiro-assistencial (Homo faber) no ambiente hospitalar, à luz do pensamento gramsciano.
Cecilia Nogueira Valenca   +5 more
doaj   +1 more source

iRNA-2OM: A Sequence-Based Predictor for Identifying 2′-O-Methylation Sites in Homo sapiens

open access: yesJ. Comput. Biol., 2018
2′-O-methylation plays an important biological role in gene expression. Owing to the explosive increase in genomic sequencing data, it is necessary to develop a method for quickly and efficiently identifying whether a sequence contains the 2′-O ...
Hui Yang   +4 more
semanticscholar   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

The latest steps of human evolution: What the hard evidence has to say about it?

open access: yesQuaternary Environments and Humans
The latest periods of human evolution are a heated topic of debate and have been at the center of paleoanthropological discussions since the beginning of the field.
Walter Neves   +4 more
doaj   +1 more source

COGNITIVE LINGUISTICS AS A METHODOLOGICAL PARADIGM [PDF]

open access: yes, 2002
A general direction in which cognitive linguistics is heading at the turn of the century is outlined and a revised understanding of cognitive linguistics as a methodological paradigm is suggest.
Kravchenko, Prof. A.V.
core  

A Good Exit: What to Do about the End of Our Species? [PDF]

open access: yes, 2018
We know that Homo sapiens will not exist forever. Given this, how should our species end? What are the reasons, if any, to delay our extinction? In this paper, I show that the pre-eminent reasons which favour prolonging the existence of the species are ...
Handfield, Toby
core   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

open access: yesAdvanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li   +8 more
wiley   +1 more source

Homo Sapiens Sapiens Meets Homo Strategicus at the Laboratory [PDF]

open access: yes
Homo Strategicus populates the vast plains of Game Theory. He knows all logical implications of his knowledge (logical omniscience) and chooses optimal strategies given his knowledge and beliefs (rationality).
Ludovic Renou, Ralph C. Bayer
core  

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