Results 91 to 100 of about 214,984 (288)

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

open access: yesAdvanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang   +7 more
wiley   +1 more source

100 mejores por materias Ranking Col-Sapiens 2012-2013:Clasificación de los mejores colegios colombianos según categoría, calidad y acreditación [PDF]

open access: yes, 2015
Objetivos: (1) publicar el listado de colegios con membresía de Sapiens Research Group; (2) el listado el listado-resumen de los 100 mejores colegios por materias.
Sapiens Research Group   +1 more
core  

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

open access: yesAdvanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu   +13 more
wiley   +1 more source

Complex Projectile Technology and Homo sapiens Dispersal into Western Eurasia.

open access: yesPaleoAnthropology, 2010
This paper proposes that complex projectile weaponry was a key strategic innovation driving Late Pleistocene human dispersal into western Eurasia after 50 Ka.
John J. Shea and Matthew L. Sisk
doaj  

THE THERMODYNAMIC AND PHYLOGENETIC FOUNDATIONS OF HUMAN WICKEDNESS

open access: yesZygon, 1985
. The problem of evil is brought under the ambit of science by explicating the theological concept “sinful” in thermo‐dynamic and phylogenetic terms, and the proposition “Homo sapiens is a sinful species” is established.
doaj   +2 more sources

Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez   +7 more
wiley   +1 more source

Coexistencia y fuentes de alimentación de mosquitos adultos (Diptera: Culicidae) en un centro de salud rural en Piura, Perú 2024

open access: yesRevista Peruana de Medicina Experimental y Salud Pública
Con el objetivo del estudio fue determinar la coexistencia y fuentes de alimentación de mosquitos adultos (Diptera: Culicidae) en un centro de salud rural de Piura en Perú, se realizó un estudio descriptivo transversal.
Archi Alejandro Ruiz Polo   +5 more
doaj   +1 more source

Expergiscere, homo "sapiens" !

open access: yes, 1996
Angelino Guido. Expergiscere, homo "sapiens" !. In: Vita Latina, N°141, 1996. pp.
Angelino, Guido
core   +1 more source

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao   +4 more
wiley   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

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