Results 191 to 200 of about 214,984 (288)

How Reusable Are Public Proteomics Datasets in Practice?

PROTEOMICS, EarlyView.
ABSTRACT Public proteomics repositories have expanded rapidly, but large‐scale reuse still depends on whether deposited studies are computationally reusable. We provide an evidence‐based snapshot of this gap by evaluating 500 non‐redundant human ProteomeXchange datasets released in 2025.
Giuseppe G. F. Leite, Victor Corasolla Carregari, Alexandre Keiji Tashima, Reinaldo Salomão   +3 more
wiley   +1 more source

Climate seasonality and predictability during the middle stone age and implications for technological diversification in early Homo sapiens. [PDF]

Sci Rep
Timbrell L, Clark J, Linares-Matás G, Boisard S, Arous EB, Blinkhorn J, Grove M, Scerri EML.   +7 more
europepmc   +1 more source

An (αβ)2 Architecture of the Arabidopsis thaliana tRNA Splicing Endonuclease Complex: Structural Modeling and Evolutionary Analyses

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The tRNA splicing endonuclease (TSEN) removes introns from precursor tRNAs (pre‐tRNAs) in eukaryotes and archaea, but the architecture and subunit organization of plant TSEN remain poorly defined. Here, we integrated in planta bimolecular fluorescence complementation (BiFC) assays with AlphaFold3 (AF3)‐based structural modeling, molecular ...
Mohammad Moniruzzaman, Markus Englert, Kazuhito Akama   +2 more
wiley   +1 more source

An Exploratory Genomic and Transcriptomic Analysis Between <i>Choloepus didactylus</i> and <i>Homo sapiens</i>. [PDF]

Genes (Basel)
Baran A, Ibrahim A, Nakano Y, Aoshima H, Ozeki T, Sato-Baran I, Ordinario DD.   +6 more
europepmc   +1 more source

Prediction of Prion Proteins in E. coli Based on Bimodal Sequence Characteristics

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prions are infectious proteins that bear misfolded conformations capable of converting folded states into misfolded aggregates under physiologically relevant conditions. In mammals, prions cause deadly maladies including Creutzfeldt‐Jakob and chronic wasting disease. To date, several prion proteins have been identified in eukaryotes, primarily
Katherine Shreeve, Jinoh Jang, Mridula Srivathsan, Siyu Li, Taylor D. Scott, Silvia Cavagnero   +5 more
wiley   +1 more source

Haplotype-Based Approach Represents Locus Specificity in the Genomic Diversification Process in Humans (Homo sapiens). [PDF]

Genes (Basel)
Shimada MK, Nishida T.
europepmc   +1 more source

Homo sapien

OpenPhysio Journal, 2022
openaire   +1 more source

Identifying resistance‐conferring cytochrome P450s in weeds: experimental strategies and practical considerations

Pest Management Science, EarlyView.
Identifying resistance‐conferring cytochrome P450s requires integrating weed characterization, gene discovery and functional validation. No single approach is sufficient to distinguish causal resistance genes from herbicide‐metabolizing enzymes. Abstract Cytochrome P450 monooxygenases (P450s) play a pivotal role in metabolic herbicide resistance, yet ...
Satoshi Iwakami, Takuya Yamaguchi
wiley   +1 more source

Identification of Novel Progesterone Receptor (PR) Inhibitors (Homo sapiens) from Metabolites of Biotransformation Fungal: A Bioinformatics Approach. [PDF]

Pharmaceuticals (Basel)
Dourado JAE, Lopes SQ, Jimenez DEQ, Ramos RS, Ferreira IM.   +4 more
europepmc   +1 more source