Results 171 to 180 of about 2,374,737 (319)

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar   +6 more
wiley   +1 more source

A Python package for fast GPU‐based proton pencil beam dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya   +4 more
wiley   +1 more source

Twelve‐month change in quantitative MRI calf muscle fat fraction in CMT1A predicts clinical change over 4 years

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessments up to four times over mean 4‐year follow‐up ...
Matthew R. B. Evans   +8 more
wiley   +1 more source

Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia ...
Zhu Guan‐Yu   +14 more
wiley   +1 more source

Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium

open access: yesAdvanced Biology, EarlyView.
The infectious potential of respiratory viruses depends on their ability to navigate through a layer of mucus that serves as a protective barrier in the lung. It is demonstrated that influenza A virus penetration through mucus is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans ...
Logan Kaler   +8 more
wiley   +1 more source

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