Results 41 to 50 of about 379,521 (267)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On a new generalization of some Hilbert-type inequalities

open access: yesOpen Mathematics, 2021
In this work, by introducing several parameters, a new kernel function including both the homogeneous and non-homogeneous cases is constructed, and a Hilbert-type inequality related to the newly constructed kernel function is established.
You Minghui, Song Wei, Wang Xiaoyu
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

On associated homogeneous Gelfand functions

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics
The paper proposes refined definitions for associated homogeneous functions (AHFs) of real variables, which are of great practical importance for a wide range of problems. I. M. Gelfand and Z. Ya.
Berdnikov Alexander   +2 more
doaj   +1 more source

ON THE ALMOST PERIODIC AT INFINITY FUNCTIONS FROM HOMOGENEOUS SPACES

open access: yesПроблемы анализа, 2018
We consider homogeneous spaces of functions defined on the real axis (or semi-axis) with values in a complex Banach space. We study the new class of almost periodic at infinity functions from homogeneous spaces.
Baskakov A. G.   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Morrey Meets Herz with Variable Exponent and Applications to Commutators of Homogeneous Fractional Integrals with Rough Kernels

open access: yesJournal of Function Spaces, 2017
We define the new central Morrey space with variable exponent and investigate its relation to the Morrey-Herz spaces with variable exponent. As applications, we obtain the boundedness of the homogeneous fractional integral operator TΩ,σ and its ...
Hongbin Wang, Jiajia Wang, Zunwei Fu
doaj   +1 more source

Lattice Sums of Homogeneous Functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1973
An asymptotic estimate for a general lattice sum is derived using Fourier analysis techniques.
openaire   +1 more source

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