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Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source

K-theory for the C*-algebras of continuous functions on certain homogeneous spaces in semi-simple Lie groups</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Cubo</i>, 2012 </span><br><span class="r_content">Estudiamos la K-teoría para las álgebras de todas las funciones continuas sobre ciertos espacios homogeneos, principalmente en los grupos de Lie conexos semi- simples y subgrupos discretos .</span><br><span class="r_sub"><i>Takahiro Sudo</i></span><br><small><a href="https://doaj.org/article/a7c1bca6d1a44bebada9d87f830ff88a" target="_blank" rel="nofollow" title="doaj.org/article/a7c1bca6d1a44bebada9d87f830ff88a">doaj</a> </small> <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70102" target="_blank" rel="nofollow">Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.</span><br><span class="r_sub"><i>Tzu‐Chieh Sun<span id="ma_3" style="display:none">, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_3')">+5 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70102?mi=2or9o2m&af=R&AllField=homogeneous space&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70102?mi=2or9o2m&af=R&AllField=homogeneous space&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_3" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70102" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70102'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70102)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_3')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/2211-5463.70078" target="_blank" rel="nofollow">Characterization of ribosome heterogeneity during endothelial to hematopoietic transition</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>FEBS Open Bio, EarlyView.</i></span><br><span class="r_content">The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic </span><br><span class="r_sub"><i>Xitong Tian<span id="ma_4" style="display:none">, Di Liu, Bing Liu, Yu Lan, Jie Zhou</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_4')">+4 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/2211-5463.70078?mi=2or9o2m&af=R&AllField=homogeneous space&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/2211-5463.70078?mi=2or9o2m&af=R&AllField=homogeneous space&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_4" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F2211-5463.70078" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/2211-5463.70078'); alert('Copied the doi');">copy doi</a> <small>(10.1002/2211-5463.70078)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_4')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1016/s0166-8641(01)00130-4" target="_blank" rel="nofollow">On power homogeneous spaces</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Topology and its Applications</i>, 2002 </span><br><span class="r_content">A topological space \(X\) is called power homogeneous if there exists a cardinal number \(\tau>0\) such that the space \(X^\tau\) is homogeneous. It may easily happen that a space \(X\) is not homogeneous while \(X\) is power homogeneous. Every first countable zero-dimensional Hausdorff space is \(\omega\)-power homogeneous.</span><br><small><a href="https://explore.openaire.eu/search/publication?pid=10.1016%2Fs0166-8641%2801%2900130-4" target="_blank" rel="nofollow" title="openaire.eu/search/publication?pid=10.1016%2Fs0166-8641%2801%2900130-4">openaire</a> </small> <div id="more_5" style="display:none"><a href="/sci_redir.php?doi=10.1016%2Fs0166-8641%2801%2900130-4" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="https://www.sciencedirect.com/science/article/pii/S0166864101001304" target="_blank" rel="nofollow" title="sciencedirect.com/science/article/pii/S0166864101001304">sciencedirect.com</a><br> <a href="javascript:navigator.clipboard.writeText('10.1016/s0166-8641(01)00130-4'); alert('Copied the doi');">copy doi</a> <small>(10.1016/s0166-8641(01)00130-4)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_5')">+2 more sources</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.5194/NHESS-6-427-2006" target="_blank" rel="nofollow">Modulation of homogeneous space-time rainfall cascades to account for orographic influences</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i></i>, 2006 </span><br><span class="r_content">The development of efficient space-time rainfall downscaling procedures is highly important for the implementation of a meteo-hydrological forecasting chain operating over small watersheds.</span><br><span class="r_sub"><i>M. G. Badas, R. Deidda, E. Piga</i></span><br><small><a href="https://www.semanticscholar.org/paper/14c4efccc7b60844cdcb039ad8ec7b8be470ec8e" target="_blank" rel="nofollow" title="semanticscholar.org/paper/14c4efccc7b60844cdcb039ad8ec7b8be470ec8e">semanticscholar</a> </small> <div id="more_6" style="display:none"><a href="/sci_redir.php?doi=10.5194%2FNHESS-6-427-2006" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.5194/NHESS-6-427-2006'); alert('Copied the doi');">copy doi</a> <small>(10.5194/NHESS-6-427-2006)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_6')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1111/j.1365-2966.2011.19399.x" target="_blank" rel="nofollow">Homogeneous studies of transiting extrasolar planets – IV. Thirty systems with space-based light curves</a> <b><a href="https://arxiv.org/pdf/1107.1235.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i></i>, 2011 </span><br><span class="r_content">I calculate the physical properties of 32 transiting extrasolar planet and brown-dwarf systems from existing photometric observations and measured spectroscopic parameters.</span><br><span class="r_sub"><i>J. Southworth</i></span><br><small><a href="https://www.semanticscholar.org/paper/031eb0d86e227b1b08694a5f46ec625d92866c23" target="_blank" rel="nofollow" title="semanticscholar.org/paper/031eb0d86e227b1b08694a5f46ec625d92866c23">semanticscholar</a> </small> <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1111%2Fj.1365-2966.2011.19399.x" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1111/j.1365-2966.2011.19399.x'); alert('Copied the doi');">copy doi</a> <small>(10.1111/j.1365-2966.2011.19399.x)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/2211-5463.70102" target="_blank" rel="nofollow">Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>FEBS Open Bio, EarlyView.</i></span><br><span class="r_content">Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...</span><br><span class="r_sub"><i>Alejandro Bernardo<span id="ma_8" style="display:none">, Natalia Díaz‐Valdivia, Patricia Fernández‐Nogueira, Jordi Alcaraz</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+3 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/2211-5463.70102?mi=2or9o2m&af=R&AllField=homogeneous space&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/2211-5463.70102?mi=2or9o2m&af=R&AllField=homogeneous space&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F2211-5463.70102" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/2211-5463.70102'); alert('Copied the doi');">copy doi</a> <small>(10.1002/2211-5463.70102)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1007/bf02505945" target="_blank" rel="nofollow">Harnack's inequality on homogeneous spaces</a> <b><a href="http://arxiv.org/pdf/funct-an/9604003v1.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Annali di Matematica Pura ed Applicata</i>, 2001 </span><br><span class="r_content">To appear in Annali di Matematica Pura e ...</span><br><span class="r_sub"><i>Remo Garattini, Remo Garattini</i></span><br><small><a href="https://explore.openaire.eu/search/publication?pid=10.1007%2Fbf02505945" target="_blank" rel="nofollow" title="openaire.eu/search/publication?pid=10.1007%2Fbf02505945">openaire</a> </small> <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.1007%2Fbf02505945" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="https://hdl.handle.net/10446/241653" target="_blank" rel="nofollow" title="hdl.handle.net/10446/241653">hdl.handle.net</a><br> <a href="http://arxiv.org/abs/funct-an/9604003" target="_blank" rel="nofollow" title="arxiv.org/abs/funct-an/9604003">arxiv.org</a><br> <a href="https://link.springer.com/content/pdf/10.1007/BF02505945.pdf" target="_blank" rel="nofollow" title="springer.com/content/pdf/10.1007/BF02505945.pdf">springer.com (pdf)</a><br> <a href="https://zbmath.org/2035092" target="_blank" rel="nofollow" title="zbmath.org/2035092">zbmath.org</a><br> <a href="javascript:navigator.clipboard.writeText('10.1007/bf02505945'); alert('Copied the doi');">copy doi</a> <small>(10.1007/bf02505945)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+5 more sources</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.3390/universe4030049" target="_blank" rel="nofollow">On Maximal Homogeneous 3-Geometries—A Polyhedron Algorithm for Space Tilings</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Universe</i>, 2018 </span><br><span class="r_content">In this paper we introduce a polyhedron algorithm that has been developed for finding space groups. In order to demonstrate the problem and the main steps of the algorithm, we consider some regular plane tilings in our examples, and then we generalize ...</span><br><span class="r_sub"><i>István Prok</i></span><br><small><a href="https://doaj.org/article/fcc1fe8c33f748aaa8a3fdc49bd4fe71" target="_blank" rel="nofollow" title="doaj.org/article/fcc1fe8c33f748aaa8a3fdc49bd4fe71">doaj</a> </small> <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.3390%2Funiverse4030049" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.3390/universe4030049'); alert('Copied the doi');">copy doi</a> <small>(10.3390/universe4030049)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-geometry/" class="suggestion"onclick="show_loader();"><b>geometry</b></a><br/><a href="/q-space_punctuation/" class="suggestion"onclick="show_loader();"><b>space punctuation</b></a><br/><a href="/q-computer_science/" class="suggestion"onclick="show_loader();"><b>computer science</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-algebra_over_a_field/" class="suggestion"onclick="show_loader();"><b>algebra over a field</b></a><br/><a href="/q-fos%3A_mathematics/" class="suggestion"onclick="show_loader();"><b>fos: mathematics</b></a><br/><a href="/q-lie_group/" class="suggestion"onclick="show_loader();"><b>lie group</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-differential_geometry_of_homogeneous_manifolds/" class="suggestion"onclick="show_loader();"><b>differential geometry of homogeneous manifolds</b></a><br/><a href="/q-operating_system/" class="suggestion"onclick="show_loader();"><b>operating system</b></a><br/><a href="/q-physics/" class="suggestion"onclick="show_loader();"><b>physics</b></a><br/></div></div></div><div class="pagenav"><a href="/q-homogeneous_space/p-10/" rel="nofollow"><b>previous</b></a> <a href="/q-homogeneous_space/p-9/" rel="nofollow">9</a> <a href="/q-homogeneous_space/p-10/" rel="nofollow">10</a> <b>11</b> <a href="/q-homogeneous_space/p-12/" rel="nofollow">12</a> <a href="/q-homogeneous_space/p-13/" rel="nofollow">13</a> <a href="/q-homogeneous_space/p-12/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> </body> </html>