Results 51 to 60 of about 183,847 (315)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

New Types of Almost Countable Dense Homogeneous Space

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2010
In 1972, Bennett studied the countable dense homogeneous (CDH) spaces and in 1992, Fitzpatrick, White, and Zhou proved that every CDH space is a T1 space.
Abdalla Tallafha, Ahmed Al-Rawashdeh
doaj   +1 more source

The regularity criterion for weak solutions to the n-dimensional Boussinesq system

open access: yesBoundary Value Problems, 2017
We consider the Boussinesq system in the homogeneous spaces of degree −1. To narrow the gap for the existence of small regular solutions in B ˙ ∞ , ∞ − 1 ( R n ) $\dot{B}^{-1}_{\infty,\infty}(\mathbb{R}^{n})$ , the biggest homogeneous space of degree −1 ...
Xiaona Cui
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Complete classification of homogeneous structures on Lorentzian direct extensions of the Heisenberg group [PDF]

open access: yesریاضی و جامعه
The Heisenberg Lie group is one of the most famous and important Lie groups among the family of three dimensional Lie groups. The direct extension of this group to the fourth dimension was taken into consideration in the study of the nilpotent Lie ...
Amirhesam Zaeim   +2 more
doaj   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

Symmetries of holomorphic geometric structures on tori

open access: yesComplex Manifolds, 2016
We prove that any holomorphic locally homogeneous geometric structure on a complex torus of dimension two, modelled on a complex homogeneous surface, is translation invariant. We conjecture that this result is true in any dimension.
Dumitrescu Sorin, McKay Benjamin
doaj   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen   +5 more
wiley   +1 more source

Spinning particle interacting with electromagnetic and antisymmetric gauge fields in anti-de Sitter space

open access: yesEuropean Physical Journal C: Particles and Fields, 2019
Massless spinning particle model that interacts with electromagnetic and antisymmetric gauge fields in anti-de Sitter space-time is considered as a constrained Hamiltonian system.
D. V. Uvarov
doaj   +1 more source

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