Results 61 to 70 of about 1,172,151 (314)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

New Types of Almost Countable Dense Homogeneous Space

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2010
In 1972, Bennett studied the countable dense homogeneous (CDH) spaces and in 1992, Fitzpatrick, White, and Zhou proved that every CDH space is a T1 space.
Abdalla Tallafha, Ahmed Al-Rawashdeh
doaj   +1 more source

Boundedness of homogeneous fractional integral operator on Morrey space

open access: yesJournal of Inequalities and Applications, 2016
For 0 < α < n ...
Siying Meng, Yanping Chen
doaj   +1 more source

Harmonic analysis on a finite homogeneous space

open access: yes, 2007
In this paper, we study harmonic analysis on finite homogeneous spaces whose associated permutation representation decomposes with multiplicity. After a careful look at Frobenius reciprocity and transitivity of induction, and the introduction of three ...
Scarabotti, Fabio, Tolli, Filippo
core   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

The regularity criterion for weak solutions to the n-dimensional Boussinesq system

open access: yesBoundary Value Problems, 2017
We consider the Boussinesq system in the homogeneous spaces of degree −1. To narrow the gap for the existence of small regular solutions in B ˙ ∞ , ∞ − 1 ( R n ) $\dot{B}^{-1}_{\infty,\infty}(\mathbb{R}^{n})$ , the biggest homogeneous space of degree −1 ...
Xiaona Cui
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Complete classification of homogeneous structures on Lorentzian direct extensions of the Heisenberg group [PDF]

open access: yesریاضی و جامعه
The Heisenberg Lie group is one of the most famous and important Lie groups among the family of three dimensional Lie groups. The direct extension of this group to the fourth dimension was taken into consideration in the study of the nilpotent Lie ...
Amirhesam Zaeim   +2 more
doaj   +1 more source

On homogeneous Hermite–Lorentz spaces [PDF]

open access: yesAsian Journal of Mathematics, 2016
We define naturally Hermite-Lorentz metrics on almost-complex manifolds as special case of pseudo-Riemannian metrics compatible with the almost complex structure. We study their isometry groups.
Ben-Ahmed, Ali, Zeghib, Abdelghani
openaire   +4 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

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