Results 111 to 120 of about 5,574,078 (353)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Mean-square continuity on homogeneous spaces of compact groups [PDF]

open access: yes, 2012
We show that any finite-variance, isotropic random field on a compact group is necessarily mean-square continuous, under standard measurability assumptions.
D. Marinucci, G. Peccati
semanticscholar   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Permanence of metric fractals

open access: yesElectronic Journal of Differential Equations, 2007
The paper studies energy functionals on quasimetric spaces, defined by quadratic measure-valued Lagrangeans. This general model of medium, known as metric fractals, includes nested fractals and sub-Riemannian manifolds.
Kyril Tintarev
doaj  

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Homogeneous ANR-spaces and Alexandroff manifolds

open access: yes, 2014
We specify a result of Yokoi \cite{yo} by proving that if $G$ is an abelian group and $X$ is a homogeneous metric $ANR$ compactum with $\dim_GX=n$ and $\check{H}^n(X;G)\neq 0$, then $X$ is an $(n,G)$-bubble.
Valov, V.
core   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

Intertwining Operators And Quantum Homogeneous Spaces

open access: yes, 1995
In the present paper the algebras of functions on quantum homogeneous spaces are studied. The author introduces the algebras of kernels of intertwining integral operators and constructs quantum analogues of the Poisson and Radon transforms for some ...
L. L. Vaksman   +5 more
core   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

open access: yesFEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian   +4 more
wiley   +1 more source

Ancient solutions of the homogenous Ricci flow on flag manifolds

open access: yesExtracta Mathematicae, 2021
For any flag manifold M=G/K of a compact simple Lie group G we describe non-collapsing ancient invariant solutions of the homogeneous unnormalized Ricci flow.
S. Anastassiou, I. Chrysikos
doaj  

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