Results 31 to 40 of about 41,379 (266)

Some Notes of Homogeneous Besov–Lorentz Spaces

Journal of Mathematics, 2023
In this paper, we consider some properties of homogeneous Besov–Lorentz spaces. First, we get some relationship between B˙p0s,q,B˙p1s,qθ,r and Besov–Lorentz spaces, and then, we obtain the scaling property of B˙p,rs,q and F˙p,rs,q.
Zhenzhen Lou
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Homogeneous Poisson Structures on Loop Spaces of Symmetric Spaces

Symmetry, Integrability and Geometry: Methods and Applications, 2008
This paper is a sequel to [Caine A., Pickrell D., Int. Math. Res. Not., to appear, arXiv:0710.4484], where we studied the Hamiltonian systems which arise from the Evens-Lu construction of homogeneous Poisson structures on both compact and noncompact type
Doug Pickrell
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Diameters of Homogeneous Spaces [PDF]

Mathematical Research Letters, 2003
Let G be a compact connected Lie group with trivial center. Using the action of G on its Lie algebra, we define an operator norm | |_{G} which induces a bi-invariant metric d_G(x,y)=|Ad(yx^{-1})|_{G} on G. We prove the existence of a constant \approx .12 (independent of G) such that for any closed subgroup H \subsetneq G, the diameter of the quotient
Freedman, Michael H., Kitaev, Alexei, Lurie, Jacob   +2 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Natural Intrinsic Geometrical Symmetries

Symmetry, Integrability and Geometry: Methods and Applications, 2009
A proposal is made for what could well be the most natural symmetrical Riemannian spaces which are homogeneous but not isotropic, i.e. of what could well be the most natural class of symmetrical spaces beyond the spaces of constant Riemannian curvature ...
Stefan Haesen, Leopold Verstraelen
doaj   +1 more source

Right amenable left group sets and the Tarski-FØlner theorem [PDF]

International Journal of Group Theory, 2017
‎We introduce right amenability‎, ‎right FØlner nets‎, ‎and right paradoxical decompositions for left homogeneous spaces and prove the Tarski-FØlner theorem for left homogeneous spaces with finite stabilisers‎.
Simon Wacker
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source