Results 41 to 50 of about 41,379 (266)

Ancient solutions of the homogenous Ricci flow on flag manifolds

open access: yesExtracta Mathematicae, 2021
For any flag manifold M=G/K of a compact simple Lie group G we describe non-collapsing ancient invariant solutions of the homogeneous unnormalized Ricci flow.
S. Anastassiou, I. Chrysikos
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Brascamp–Lieb Inequalities on Compact Homogeneous Spaces

open access: yesAnalysis and Geometry in Metric Spaces, 2019
We provide a general strategy to construct multilinear inequalities of Brascamp–Lieb type on compact homogeneous spaces of Lie groups. As an application we obtain sharp integral inequalities on the real unit sphere involving functions with some degree of
Bramati Roberto
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Curvatures on Homogeneous Generalized Matsumoto Space

open access: yesMathematics, 2023
The curvature characteristics of particular classes of Finsler spaces, such as homogeneous Finsler spaces, are one of the major issues in Finsler geometry. In this paper, we have obtained the expression for S-curvature in homogeneous Finsler space with a
M. K. Gupta   +3 more
doaj   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

From homogeneous metric spaces to Lie groups

open access: yesComptes Rendus. Mathématique
We study homogeneous metric spaces, by which we mean connected, locally compact metric spaces whose isometry group acts transitively.After a review of a number of classical results, we use the Gleason–Iwasawa–Montgomery–Yamabe–Zippin structure theory to ...
Cowling, Michael G.   +4 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

POINTWISE MULTIPLICATION IN THE REALIZED HOMOGENEOUS BESOV AND TRIEBEL-LIZORKIN SPACES

open access: yesПроблемы анализа, 2018
For either homogeneous Besov spaces B_(s;p,q)(R_n) or homogeneous Triebel-Lizorkin spaces F_(s;p,q)(R_n), with the conditions either s < n/p, or s = n/p and q ≤ 1 in the B_(s;p,q)-case, p ≤ 1 in the F_(s;p,q)-case, we prove some pointwise multiplication ...
Madani Moussai, Samira Bissar
doaj   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

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