Results 61 to 70 of about 5,309,720 (337)

Balanced line bundles and equivariant compactifications of homogeneous spaces [PDF]

open access: yes, 2013
Manin's conjecture predicts an asymptotic formula for the number of rational points of bounded height on a smooth projective variety in terms of its global geometric invariants.
B. Hassett, Sho Tanimoto, Y. Tschinkel
semanticscholar   +1 more source

On Holonomy and Homogeneous Spaces [PDF]

open access: yesNagoya Mathematical Journal, 1957
In general a homogeneous space admits many invariant affine connections. Among these are certain connections which appear in many ways to be more natural than the others. We refer to the connections which K. Nomizu in [4] calls canonical affine connections of the first kind.
openaire   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Warped product Einstein metrics on homogeneous spaces and homogeneous Ricci solitons [PDF]

open access: yes, 2013
In this paper we consider connections between Ricci solitons and Einstein metrics on homogeneous spaces. We show that a semi-algebraic Ricci soliton admits an Einstein one-dimensional extension if the soliton derivation can be chosen to be normal.
Chenxu He, P. Petersen, W. Wylie
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Natural Intrinsic Geometrical Symmetries

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2009
A proposal is made for what could well be the most natural symmetrical Riemannian spaces which are homogeneous but not isotropic, i.e. of what could well be the most natural class of symmetrical spaces beyond the spaces of constant Riemannian curvature ...
Stefan Haesen, Leopold Verstraelen
doaj   +1 more source

Right amenable left group sets and the Tarski-FØlner theorem [PDF]

open access: yesInternational Journal of Group Theory, 2017
‎We introduce right amenability‎, ‎right FØlner nets‎, ‎and right paradoxical decompositions for left homogeneous spaces and prove the Tarski-FØlner theorem for left homogeneous spaces with finite stabilisers‎.
Simon Wacker
doaj   +1 more source

Neighborhoods of subvarieties in homogeneous spaces [PDF]

open access: yes, 2013
We study the holomorphic/meromorphic function theory and the fundamental group of Euclidean open neighborhoods of compact subvarieties in homogeneous spaces; building on results of Hironaka, Hartshorne, Napier and Ramachandran in the ample normal bundle ...
J. Kollár
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Strongly homogeneous spaces [PDF]

open access: yesProceedings of the American Mathematical Society, 1975
Spaces satisfying various conditions have previously been called strongly homogeneous spaces and many results about the group of homeomorphisms of such spaces have been proved. However spaces may satisfy some “strongly homogeneous” condition without being homogeneous.
openaire   +1 more source

Home - About - Disclaimer - Privacy