Results 241 to 250 of about 388,221 (319)

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

open access: yesAdvanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao   +6 more
wiley   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow   +6 more
wiley   +1 more source

Effect of Fe and Si Content on Microstructure and Properties of Al-Cu-Li Alloys. [PDF]

open access: yesMaterials (Basel)
Feng T   +11 more
europepmc   +1 more source

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song   +17 more
wiley   +1 more source

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