Results 291 to 300 of about 374,721 (319)

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Immersed isogeometric analysis with boundary conformal quadrature for finite deformation elasticity. [PDF]

Arch Appl Mech
Elbadry YT, Antolín P, Weeger O.
europepmc   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Double emulsion templated monodisperse antibubbles via combined high-shear homogenization and T-junction microfluidics. [PDF]

Sci Rep
Niroula A, Zia R, Poortinga A, Nazir A.
europepmc   +1 more source

Impact of soft tissue homogenization methods on RNA quality. [PDF]

Mol Biol Rep
Ostapowicz J, Maćkowiak B, Ostrowska K, Kaczmarek B, Pietras N, Frąckowiak D, Fundowicz M, Kulcenty K, Golusiński W, Suchorska W.   +9 more
europepmc   +1 more source

rRNA loss induced by rifampicin addition in Escherichia coli reflects extraction artifacts rather than in vivo degradation. [PDF]

Sci Rep
Burck M, Nouaille S, Carpousis AJ, Cocaign-Bousquet M, Girbal L.   +4 more
europepmc   +1 more source

Nanocrystalline Drug Delivery Systems for Natural Compounds: Progress, Challenges and Future Opportunities. [PDF]

Int J Nanomedicine
Ji M, Long L, Xiong S, Liu Z, Luo J, Liu D.   +5 more
europepmc   +1 more source

The Feasibility of Artificial Intelligence and Raman Spectroscopy for Determining the Authenticity of Minced Meat. [PDF]

Foods
Nedeljkovic A, Maggiolino A, Rocchetti G, Sun W, Heinz V, Tomasevic ID, Djordjevic V, Tomasevic I.   +7 more
europepmc   +1 more source