Results 71 to 80 of about 362,453 (271)

Discrete Geometric Structures in Homogenization and Inverse Homogenization with application to EIT [PDF]

, 2009
We introduce a new geometric approach for the homogenization and inverse homogenization of the divergence form elliptic operator with rough conductivity coefficients $\sigma(x)$ in dimension two.
Desbrun, Mathieu, Donaldson, Roger D., Owhadi, Houman   +2 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Magnetic transmission gear finite element simulation with iron pole hysteresis

Open Physics, 2018
Ferromagnetic poles in a magnetic transmission gear require particular attention during their design process. Usually, during the numerical simulation of these devices the effects of hysteresis for loss estimation are neglected and considered only during
Filippini Mattia, Alotto Piergiorgio, Glehn Gregor, Hameyer Kay   +3 more
doaj   +1 more source

Modeling and analysis of loaded multilayered magnetoelectroelastic structures composite materials: Applications

Advanced Electromagnetics, 2016
This paper presents the detailed analysis of fiber- reinforced magnetoelectroelastic composite plates. The work is divided into two major sections. The first one deals with the homogenization of the properties of each layer based on the Mori-Tanaka mean ...
M. Ajdour, A. Bakkali, L. Azrar, A. El Omri   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

$N$-homogeneous superalgebras

Journal of Noncommutative Geometry, 2008
We develop the theory of N -homogeneous algebras in a super-setting, with particular emphasis on the Koszul property. To any Hecke operator \mathcal R on a vector ...
Hai, Phùng Hô, Kriegk, Benoît, Lorenz, Martin   +2 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

New homogenization approaches for stochastic transport through heterogeneous media

, 2019
The diffusion of molecules in complex intracellular environments can be strongly influenced by spatial heterogeneity and stochasticity. A key challenge when modelling such processes using stochastic random walk frameworks is that negative jump ...
Carr, Elliot J., Simpson, Matthew J.
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Tailoring Effective Media by Mie Resonances of Radially-Anisotropic Cylinders

Photonics, 2015
This paper studies constructing advanced effective materials using arrays of circular radially-anisotropic (RA) cylinders. Homogenization of such cylinders is considered in an electrodynamic case based on Mie scattering theory.
Henrik Kettunen, Henrik Wallén, Ari Sihvola   +2 more
doaj   +1 more source