Results 81 to 90 of about 374,721 (319)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Bingham flow in porous media with obstacles of different size

open access: yes, 2017
By using the unfolding operators for periodic homogenization, we give a general compactness result for a class of functions defined on bounded domains presenting perforations of two different size.
Bunoiu, Renata, Cardone, Giuseppe
core   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

open access: yesFEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli   +4 more
wiley   +1 more source

Stochastic homogenization of viscous Hamilton-Jacobi equations and applications

open access: yes, 2013
We present stochastic homogenization results for viscous Hamilton-Jacobi equations using a new argument which is based only on the subadditive structure of maximal subsolutions (solutions of the "metric problem").
Armstrong, Scott N., Tran, Hung V.
core   +2 more sources

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Homogeneous ENR's

open access: yesTopology and its Applications, 1987
The following result is proved: Theorem. Let X be a homogeneous, n- dimensional ENR and suppose that the local homology groups \(H_*(X,X- \{x\};{\mathbb{Z}})\) (x\(\in X)\) are finitely generated. Then X is a homology n-manifold. (Reviewer's remarks: The author apparently wasn't aware of a more general result proved by \textit{G. E.
openaire   +3 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Multiscale and Failure Analysis of Periodic Lattice Structures

open access: yesApplied Sciences
A full-cycle, multiscale analysis technique was developed for periodic lattice structures with geometric repetition, aiming for more efficient modeling to predict their failure loads.
Young Kwon, Matthew Minck
doaj   +1 more source

Mori-Tanaka Based Estimates of Effective Thermal Conductivity of Various Engineering Materials

open access: yesMicromachines, 2011
The purpose of this paper is to present a simple micromechanics-based model to estimate the effective thermal conductivity of macroscopically isotropic materials of matrix-inclusion type.
Michal Šejnoha   +3 more
doaj   +1 more source

Theoretical and numerical analysis of current-driven electromagnetic homogenization and the problem of effective medium parameters for finite samples

open access: yes, 2013
Reflection and refraction of electromagnetic waves by artificial periodic composites (metamaterials) can be accurately modeled by an effective medium theory only if the boundary of the medium is explicitly taken into account and the two effective ...
Markel, Vadim A., Tsukerman, Igor
core   +1 more source

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