Results 101 to 110 of about 53,900 (301)

Towards implementing climate services in Peru – The project CLIMANDES

Climate Services, 2016
CLIMANDES is a pilot twinning project between the National Weather Services of Peru and Switzerland (SENAMHI and MeteoSwiss), developed within the Global Framework for Climate Services of the World Meteorological Organization (WMO). Split in two modules,
G. Rosas, S. Gubler, C. Oria, D. Acuña, G. Avalos, M. Begert, E. Castillo, M. Croci-Maspoli, F. Cubas, M. Dapozzo, A. Díaz, D. van Geijtenbeek, M. Jacques, T. Konzelmann, W. Lavado, A. Matos, F. Mauchle, M. Rohrer, A. Rossa, S.C. Scherrer, M. Valdez, M. Valverde, G. Villar, E. Villegas   +23 more
doaj   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Systematic Physics Constrained Parameter Estimation of Stochastic Differential Equations

, 2014
A systematic Bayesian framework is developed for physics constrained parameter inference ofstochastic differential equations (SDE) from partial observations.
Franzke, Christian L. E., Peavoy, Daniel, Roberts, Gareth O.   +2 more
core   +1 more source

Global analysis of night marine air temperature and its uncertainty since 1880: the HadNMAT2 Dataset [PDF]

, 2013
An updated version of the Met Office Hadley Centre’s monthly night marine air temperature dataset is presented. It is available on a 5? latitude-longitude grid from 1880 as anomalies relative to 1961-1990 calendar-monthly climatological average night ...
Allan, Berry, Berry, Berry, Berry, Boyer, Brohan, Brohan, Chenoweth, Compo, Dixon, Dyer, Embury,, Fairall, Haimberger, Hansen, Ishii, Jones, Kaplan, Kennedy, Kennedy, Kent, Large, Lindsay, Marshall, Menne, Morice, Parker, Rayner, Rayner, Smith, Smith, Smith, Thompson, Thorne, Wilkinson, Woodruff, Woodruff, Woodruff, Worley   +39 more
core   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Dry and wet periods in the northwestern Maghreb for present day and future climate conditions

Meteorologische Zeitschrift, 2008
One urgent issue of climate research is the regional downscaling of global-scale climate scenarios. The present study, which is part of the research of the IMPETUS West-Africa project, shows an analysis of wet and dry periods in north-western Africa both
Kai Born, Andreas H. Fink, Heiko Paeth
doaj   +1 more source

Averaging versus Chaos in Turbulent Transport? [PDF]

, 2004
In this paper we analyze the transport of passive tracers by deterministic stationary incompressible flows which can be decomposed over an infinite number of spatial scales without separation between them.
Owhadi, Houman
core   +3 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Carbonate alteration of ophiolitic rocks in the Arabian–Nubian Shield of Egypt: sources and compositions of the carbonating fluid and implications for the formation of Au deposits [PDF]

, 2016
Ultramafic portions of ophiolitic fragments in the Arabian–Nubian Shield (ANS) show pervasive carbonate alteration forming various degrees of carbonated serpentinites and listvenitic rocks.
Azer, Mokhles K., Boskabadi, Arman, Boyce, Adrian, Broman, Curt, Cooper, Matthew J., Majka, Jaroslaw, Mohamed, Fathy H., Pitcairn, Iain K., Stern, Robert J., Teagle, Damon A.H.   +9 more
core   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source