Results 111 to 120 of about 53,900 (301)

Environmental and microbial factors shape dissolved organic matter across multiple ecosystems

open access: yesCommunications Earth & Environment
Dissolved organic matter, one of the largest carbon pools in aquatic ecosystems, plays a critical role in global carbon cycling, yet how its composition shifts across Earth’s main ecosystems remains unclear. Here, we tracked its changes along the aquatic
Bixi Guo   +6 more
doaj   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

CREST: a Climate Data Record of Stratospheric Aerosols [PDF]

open access: yesEarth System Science Data
Climate-related studies need information about the distribution of stratospheric aerosols, which influence the energy balance of the Earth's atmosphere.
V. F. Sofieva   +8 more
doaj   +1 more source

International ethics and globalization [PDF]

open access: yes, 2011
In the inherently anarchic international system the validity of moral principles is weakening. To overcome anarchy global governance is needed. It means efficient international institutions, but also pressures from the global civil society and the self ...
Boda, Zsolt
core  

Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota

open access: yesAdvanced Science, EarlyView.
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo   +11 more
wiley   +1 more source

An Assessment of the Impact of Climate Change on Maize Production in Northern Mexico

open access: yesAtmosphere
Maize yield is highly sensitive to climate change and extreme weather events. In some locations, it is projected to decrease due to an increase in the average growing season temperature. The present study analyzes changes in temperature and precipitation
Nuria Aide López Hernández   +4 more
doaj   +1 more source

Two decades of homogenized satellite ozone measurements for climate services [PDF]

open access: green, 2018
Since the launch of GOME onboard ERS-2 in 1995 total and tropospheric ozone have been derived from European satellite instruments. In the framework of the ESA CCI and the EU ECMWF C3S projects, BIRA generates total ozone products from the satellite sensors GOME, SCIAMACHY, OMI, and GOME-2 using the GODFIT algorithm and DLR is responsible for ...
Klaus-Peter Heue   +6 more
openalex   +2 more sources

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu   +6 more
wiley   +1 more source

Monitoring changes in precipitation and radiative energy using satellite data and climate models [PDF]

open access: yes, 2009
Current changes in the tropical hydrological cycle, including water vapour and precipitation, are presented over the period 1979-2008 based on a diverse suite of observational datasets and atmosphere-only climate models.
Allan, R.P., John, V.O.
core  

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

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