Results 171 to 180 of about 478 (210)

Redirecting a Native Ene‐Reductase Toward Desaturation With Reverse Enantioselectivity

Angewandte Chemie, EarlyView.
A native ene‐reductase, XenA, was repurposed to catalyze the reverse‐enantioselective desaturation of cyclohexanones. The final variant was obtained through extensive protein engineering, combining PROSS‐guided computational design with mutagenesis and screening.
Qing‐Qing Zeng, Cristina Berga, Carla Calvó‐Tusell, Marc Garcia‐Borràs, Zhen Liu   +4 more
wiley   +2 more sources

Almost Global Existence for Some Hamiltonian PDEs with Small Cauchy Data on General Tori. [PDF]

Commun Math Phys
Bambusi D, Feola R, Montalto R.
europepmc   +1 more source

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding, Dylan Hamitouche, Simon Thebault, Patrick Kearns, Ahmed Abdelhak, Adil Harroud   +5 more
wiley   +1 more source

Color‐Pure Organic Luminophores: Characteristics, Definitions, Physical Basis and Fundamental Design Principles

Angewandte Chemie, EarlyView.
Color‐pure all‐organic emitters, i.e., with narrow spectral characteristics, are intensively studied for high‐definition organic LEDs and multi‐color bioimaging. In order to guide targeted materials design, this educative review discusses spectral characteristics, proper definitions and units, and the physical basis of spectral broadening, to distill ...
Johannes Gierschner, Sunwu Song, Siyang Feng, Liangxuan Wang, Miguel Ródenas, Begoña Milián‐Medina, Min Sang Kwon   +6 more
wiley   +2 more sources

Topology-preserving Hodge decomposition in the Eulerian representation. [PDF]

Beijing J Pure Appl Math
Su Z, Tong Y, Wei GW.
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Expected Complexity of Barcode Reduction. [PDF]

J Appl Comput Topol
Giunti B, Houry G, Kerber M, Söls M.
europepmc   +1 more source

Spectral Networks and Stability Conditions for Fukaya Categories with Coefficients. [PDF]

Commun Math Phys
Haiden F, Katzarkov L, Simpson C.
europepmc   +1 more source

Synthesis and Interfacial Behavior of Mixed Potassium N‐Lauroyl/N‐Myristoyl Glycinate Surfactants With Varying Alkyl Chain Ratios

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Biodegradable and low‐irritant amino acid–based surfactants have attracted considerable attention as environmentally friendly alternatives to conventional petroleum‐derived surfactants. In this study, a series of acyl amino acid surfactants with identical amino acid head groups but different alkyl chain lengths were synthesized via a modified ...
Toshihiro Takeshita, Tanjina Sharmin, Atsuki Nishihara, Sihyung Kim, Kazusa Mishima, Sahena Ferdosh, Agus Saptoro, Hussein Znad, Zaidul Islam Sarker, Kai Bin Liew, Mikio Ouchi, Kenji Mishima   +11 more
wiley   +1 more source

Dory: Computation of persistence diagrams up to dimension two for Vietoris-Rips filtrations of large data sets. [PDF]

J Comput Sci
Aggarwal M, Periwal V.
europepmc   +1 more source