Results 111 to 120 of about 218,555 (316)
Recombination processes and non-linear Markov chains [PDF]
arXiv, 2013 Bacteria are known to exchange genetic information by horizontal gene transfer. Since the frequency of homologous recombination depends on the similarity of recombining segments, several studies examined whether this could lead to the emergence of subspecies.
arxiv
Advanced Science, EarlyView.This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang +13 more
wiley +1 more source
Food Bioengineering, Volume 1, Issue 3-4, Page 205-211, December 2022., 2022 1. To eliminate the extensively accumulated by‐product N‐acetylglucosamine (GlcNAc), the UDP‐GlcNAc epimerase (NeuC) pathway without GlcNAc production was firstly reconstructed and optimized in Bacillus subtilis, and thereby NeuAc titer increased to 5.9 g/L and the by‐product GlcNAc was eliminated. 2.
Haoyu Guo +6 more
wiley +1 more source
Advanced Science, EarlyView.CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang +14 more
wiley +1 more source
Oligonucleotide-Mediated, PCR-Independent Cloning by Homologous Recombination
BioTechniques, 2001 We have developed an oligonucleotide-mediated cloning technique based on homologous recombination in Saccharomyces cerevisiae that allows precise DNA sequences to be transferred independent of restriction enzymes and PCR.
D.J. DeMarini +6 more
doaj +1 more source
RECOMBINATION BETWEEN SUPPOSEDLY HOMOLOGOUS CHROMOSOMES OF GOSSYPIUM BARBADENSE L. AND G. HIRSUTUM L [PDF]
, 1961 S. G. Stephens
openalex +1 more source
Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations
Advanced Science, EarlyView.Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou +6 more
wiley +1 more source
CRISPR/Cas Gene Editing of a Large DNA Virus: African Swine Fever Virus
Bio-Protocol, 2018 Gene editing of large DNA viruses, such as African swine fever virus (ASFV), has traditionally relied on homologous recombination of a donor plasmid consisting of a reporter cassette with surrounding homologous viral DNA.
Manuel Borca +4 more
doaj +1 more source
The length of the homologous pairing region for genetic recombination in bacteriophage T4. [PDF]
, 1967 John W. Drake
openalex +1 more source
Direct Quantification of Protein–Protein Interactions in Living Bacterial Cells
Advanced Science, EarlyView.Quantitative measurement of protein–protein interactions in living cells is vital for biotechnology applications. Fluorescence resonance energy transfer (FRET) signals in bacterial cells are often weak, leading to false‐positive. Quantitative FRET measurements are implemented to overcome the weak FRET signal.
Soojung Yi +12 more
wiley +1 more source