Co‐Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement
Advanced Science, EarlyView.This study finds that large‐fruited tomatoes accumulate less cadmium (Cd) compared to wild tomatoes and cherry tomatoes. This is because, during the improvement process of tomato, the low‐Cd allele LCT1A and the large fruit allele fw3.2T are closely linked, leading to a co‐selection event.
Xingyu Zhang +11 more
wiley +1 more source
Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]
, 2018 Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core +1 more source
The length of the homologous pairing region for genetic recombination in bacteriophage T4. [PDF]
, 1967 John W. Drake
openalex +1 more source
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Advanced Science, EarlyView.Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan +15 more
wiley +1 more source
eLife, 2014 The activation induced cytidine deaminase (AID) protein is known to initiate somatic hypermutation, gene conversion or switch recombination by cytidine deamination within the immunoglobulin loci.
Jean-Marie Buerstedde +2 more
doaj +1 more source
A change of view: homologous recombination at single-molecule resolution
Nature reviews genetics, 2017 Genetic recombination occurs in all organisms and is vital for genome stability. Indeed, in humans, aberrant recombination can lead to diseases such as cancer.
Kyle Kaniecki, L. Tullio, E. Greene
semanticscholar +1 more source
GmSop20 Functions as a Key Coordinator of the Oil‐To‐Protein Ratio in Soybean Seeds
Advanced Science, EarlyView.This study investigates the seed oil‐to‐protein ratio as a comprehensive quality metric and identifies GmSop20 as a crucial regulatory gene through forward genetics methodologies. By integrating GmSop20 with superior haplotypes and using gene editing/overexpression, new strategies are provided for precisely tuning the seed oil‐to‐protein ratio, thereby
Haowei Zheng +17 more
wiley +1 more source
Oligonucleotide-Mediated, PCR-Independent Cloning by Homologous Recombination
BioTechniques, 2001 We have developed an oligonucleotide-mediated cloning technique based on homologous recombination in Saccharomyces cerevisiae that allows precise DNA sequences to be transferred independent of restriction enzymes and PCR.
D.J. DeMarini +6 more
doaj +1 more source
RecA + -Dependent Repair of Gamma-Ray Damage to Escherichia coli Does Not Require Recombination Between Existing Homologous Chromosomes [PDF]
, 1971 B.A. Bridges
openalex +1 more source
BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43
Advanced Science, EarlyView.This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan +13 more
wiley +1 more source