Results 321 to 330 of about 773,827 (377)

Nuclear-Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance. [PDF]

Adv Sci (Weinh)
Liu H, Feng J, Pan T, Zhang P, Ye L, Jiang Z, Zhou Z, Mao Q, Li J, Yang X, Gao P, Huang, Zhang H.   +12 more
europepmc   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

Pest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian, Hua Zhou, Zhenxing Zhao, Yongjiang Zhang, Wenjun Zhao, Lulu Cai, Tao Guo   +6 more
wiley   +1 more source

Prognostic nomogram for advanced epithelial ovarian cancer in the era of homologous recombination testing and PARP inhibitor therapy. [PDF]

Am J Cancer Res
Lin H, Ou YC, Fu HC, Tsai CC, Wang YW, Chen YY, Huang SW, Wu CH.   +7 more
europepmc   +1 more source

Threshold Concepts and Concept Networks in Evolution Education: An Experimental Intervention Study

Science Education, EarlyView.
ABSTRACT This study analyzes the effect of different instructions on threshold concepts within material covering natural selection on students' use of concepts about evolution. Moreover, it examines students' use of concepts as interconnected networks when reasoning about natural selection and analyzes how these concepts relate to each other regarding ...
Helena Aptyka, Daniela Fiedler, Jörg Großschedl   +2 more
wiley   +1 more source

Insights From Nonsense-Mediated mRNA Decay for Prognosis in Homologous Recombination-Deficient Ovarian Cancer. [PDF]

Cancer Sci
Han L, Liu J, Zhang R, Cheng Y, Dong L, Wei L, Liu J, Wang K, Yu J.   +8 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

HRProfiler Detects Homologous Recombination Deficiency in Breast and Ovarian Cancers Using Whole-Genome and Whole-Exome Sequencing Data. [PDF]

Cancer Res
Abbasi A, Steele CD, Bergstrom EN, Khandekar A, Farswan A, McKay RR, Pillay N, Alexandrov LB.   +7 more
europepmc   +1 more source

Structural Tuning of Layered Perovskites for Enhanced Broadband Emission at Room Temperature

Small Structures, EarlyView.
This study shows how changes in organic cation–solvent interactions disrupt the conventional Ruddlesden–Popper layered perovskite structure, leading to corner‐sharing disconnected ribbon‐like perovskites with broadband white light emission and grooves that enable localized Mn doping.
Aarya Prabhakaran, Quentin Evrard, Danilo Marchetti, Sirous Khabbaz Abkenar, Luiz Gustavo Bonato, Balaji Dhanabalan, Iryna Andrusenko, Simone Lauciello, Pavlo Solokha, Serena De Negri, Luca Goldoni, Moussa D. Faye Diouf, Liberato Manna, Giorgio Divitini, Mauro Gemmi, Milena P. Arciniegas   +15 more
wiley   +1 more source

Multiomics analysis of homologous recombination deficiency across cancer types. [PDF]

Biomol Biomed
Dong L, Li L, Zhu L, Xu F, Zhang R, Li Q, Zhu Y, Zeng Z, Ding K.   +8 more
europepmc   +1 more source

CRISPR-Cas targeting in Haloferax volcanii promotes within-species gene exchange by triggering homologous recombination

Choudhary DK, Turgeman-Grott I, Robinzon S, Gophna U.   +3 more
europepmc   +1 more source