Results 321 to 330 of about 766,679 (374)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Prp19/CDC5L promotes gastric cancer via activation of the MAPK pathway-mediated homologous recombination. [PDF]

Int J Biol Sci
Qiu S, Wang F, Gao X, Guan W, Dai T, Yin L, Wang F, Sun J, Guo P, Wu H, Feng S, Tang C.   +11 more
europepmc   +1 more source

From Single to Multi‐Material 3D Printing of Glass‐Ceramics for Micro‐Optics

Small Methods, EarlyView.
This article explores advancements in two‐photon lithography (TPL) for fabricating high‐refractive‐index micro‐optics. It examines single and multi‐material 3D architectures in glass and ceramics (GLACEs), highlighting photoresin customization, critical fabrication conditions, and cross‐scale structural and optical characterization.
Joel Arriaga‐Dávila, Cristian Rosero‐Arias, Dirk Jonker, Margoth Córdova‐Castro, Josua Zscheile, Robert Kirchner, Alan Aguirre‐Soto, Robert Boyd, Israel De Leon, Han Gardeniers, Arturo Susarrey‐Arce   +10 more
wiley   +1 more source

Boosting CRISPR-Cas9 efficiency through enhanced homologous recombination. [PDF]

Mol Ther Nucleic Acids
Kim SH, Yoon S, Kim KP.
europepmc   +1 more source

Exome‐wide molecular insights from blood and urine liquid biopsies in genitourinary cancers

UroPrecision, EarlyView.
Abstract Background Liquid biopsy has emerged as a non‐invasive method for real‐time cancer monitoring especially in genitourinary (GU) oncology. Most current studies utilize a panel‐based molecular profiling ranging from 50–600 genes; however, a comprehensive exome‐wide profiling of real‐world patient samples has been lacking. Methods Over 2000 liquid
Eric Jia, Tiantian Zheng, Yong Huang, Pan Du   +3 more
wiley   +1 more source

Repression of PFKFB3 sensitizes ovarian cancer to PARP inhibitors by impairing homologous recombination repair. [PDF]

Cell Commun Signal
Xiao Y, Wu Y, Wang Q, Li M, Deng C, Gu X.   +5 more
europepmc   +1 more source

Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes. [PDF]

Front Pharmacol
Zhong J, Liang L, Zhao N, Wang J, Shu P.
europepmc   +1 more source

Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination. [PDF]

Nature
Salunkhe S, Daley JM, Kaur H, Tomimatsu N, Xue C, Raina VB, Jasper AM, Rogers CM, Li W, Zhou S, Mojidra R, Kwon Y, Fang Q, Ji JH, Badamchi Shabestari A, Fitzgerald O, Dinh H, Mukherjee B, Habib AA, Hromas R, Mazin AV, Wasmuth EV, Olsen SK, Libich DS, Zhou D, Zhao W, Greene EC, Burma S, Sung P.   +28 more
europepmc   +1 more source

Genomic landscape and homologous recombination repair deficiency signature in stage I-III and de novo stage IV primary breast cancers. [PDF]

Oncologist
Jeon JE, Chen KT, Madison R, Schrock AB, Sokol E, Levy MA, Rozenblit M, Huang RSP, Pusztai L.   +8 more
europepmc   +1 more source