Results 331 to 340 of about 773,827 (377)

Optimizing Yeast Homologous Recombination for Splicing Large Coronavirus Genome Fragments. [PDF]

Int J Mol Sci
Xiong G, Huang X, Hu A, Meng Z, Cui J, Feng Y, Chen Z, Lu Y, Yang Q, Liu G.   +9 more
europepmc   +1 more source

Irinotecan alleviates chemoresistance to anthracyclines through the inhibition of AARS1-mediated BLM lactylation and homologous recombination repair. [PDF]

Signal Transduct Target Ther
Li X, Zhang C, Mei Y, Zhong W, Fan W, Liu L, Feng Z, Bai X, Liu C, Xiao M, He W, Lin T, Gou X.   +12 more
europepmc   +1 more source

Clinical-genomic characteristics of homologous recombination deficiency (HRD) in breast cancer: application model for practice. [PDF]

Eur J Med Res
Du J, Zhu L, Duan C, Ma N, Zhou Y, Li D, Zhang J, Zhang J, Wang Y, Liu X, Ren Y, Wang B.   +11 more
europepmc   +1 more source

Assay for Site-Specific Homologous Recombination Activity in Adherent Cells, Suspension Cells, and Tumor Tissues. [PDF]

Bio Protoc
Yoshino Y, Kikuta S, Chiba N.
europepmc   +1 more source

Evaluation of two algorithms measuring homologous recombination deficiency status in prognostic assessment for treatment-naïve non-small cell lung cancer. [PDF]

Chin J Cancer Res
Ma Y, Huang J, He L, Du J, Liu L, Li X, Jiao P, Wu X, Zhou W, Xu X, Yang L, Di J, Zhu C, Li L, Liu D, Wang Z.   +15 more
europepmc   +1 more source

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Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer.

New England Journal of Medicine, 2023
BACKGROUND Helicobacter pylori infection is a well-known risk factor for gastric cancer. However, the contribution of germline pathogenic variants in cancer-predisposing genes and their effect, when combined with H.
Y. Usui, Yukari Taniyama, Mikiko Endo, Yuriko N. Koyanagi, Y. Kasugai, I. Oze, Hidemi Ito, I. Imoto, Tsutomu Tanaka, M. Tajika, Y. Niwa, Y. Iwasaki, T. Aoi, N. Hakozaki, Sadaaki Takata, Kunihiko Suzuki, C. Terao, M. Hatakeyama, M. Hirata, K. Sugano, Teruhiko Yoshida, Y. Kamatani, H. Nakagawa, K. Matsuda, Yoshinori Murakami, A. Spurdle, K. Matsuo, Y. Momozawa   +27 more
semanticscholar   +1 more source

Innovation by homologous recombination

Current Opinion in Chemical Biology, 2013
Swapping fragments among protein homologs can produce chimeric proteins with a wide range of properties, including properties not exhibited by the parents. Computational methods that use information from structures and sequence alignments have been used to design highly functional chimeras and chimera libraries.
Trudeau, Devin L., Smith, Matthew A., Arnold, Frances H.   +2 more
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Homologous Recombination in Eukaryotes

2012
Homologous recombination (HR) is a mechanistically conserved pathway that ensures maintenance of genomic integrity. During meiosis, HR results in DNA crossover events between homologous chromosomes that produce the genetic diversity inherent in germ cells.
Richard Fishel, Ravindra Amunugama
openaire   +3 more sources