Results 331 to 340 of about 766,679 (374)

Comprehensive analysis of the mitochondrial genome of <i>Iris domestica</i> emphasizing multichromosomal organization and repeat-mediated homologous recombination. [PDF]

Front Plant Sci
Ouyang L, Li X, Wang R, Chen Y, Wang S, Wang J, Tian Y.   +6 more
europepmc   +1 more source

Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair. [PDF]

Nucleic Acids Res
Hung SH, Liang Y, Heyer WD.
europepmc   +1 more source

The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination

Burlet D, Khan MM, Hacot S, Buthmann H, Bardoulet L, Huber A, Gorry J, Lopez BS, Couté Y, Geyer M, Tissier A, Petrilli V.   +11 more
europepmc   +1 more source

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Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer.

New England Journal of Medicine, 2023
BACKGROUND Helicobacter pylori infection is a well-known risk factor for gastric cancer. However, the contribution of germline pathogenic variants in cancer-predisposing genes and their effect, when combined with H.
Y. Usui, Yukari Taniyama, Mikiko Endo, Yuriko N. Koyanagi, Y. Kasugai, I. Oze, Hidemi Ito, I. Imoto, Tsutomu Tanaka, M. Tajika, Y. Niwa, Y. Iwasaki, T. Aoi, N. Hakozaki, Sadaaki Takata, Kunihiko Suzuki, C. Terao, M. Hatakeyama, M. Hirata, K. Sugano, Teruhiko Yoshida, Y. Kamatani, H. Nakagawa, K. Matsuda, Yoshinori Murakami, A. Spurdle, K. Matsuo, Y. Momozawa   +27 more
semanticscholar   +1 more source

Innovation by homologous recombination

Current Opinion in Chemical Biology, 2013
Swapping fragments among protein homologs can produce chimeric proteins with a wide range of properties, including properties not exhibited by the parents. Computational methods that use information from structures and sequence alignments have been used to design highly functional chimeras and chimera libraries.
Trudeau, Devin L., Smith, Matthew A., Arnold, Frances H.   +2 more
openaire   +4 more sources

Homologous Recombination in Eukaryotes

2012
Homologous recombination (HR) is a mechanistically conserved pathway that ensures maintenance of genomic integrity. During meiosis, HR results in DNA crossover events between homologous chromosomes that produce the genetic diversity inherent in germ cells.
Richard Fishel, Ravindra Amunugama
openaire   +3 more sources

Hotspots of homologous recombination

Experientia, 1994
Homologous recombination occurs at higher than average frequency at and near hotspots. Hotspots are special nucleotide sequences recognized by proteins that promote, directly or indirectly, a rate limiting step of recombination. This review focuses on two well-studied examples, the Chi sites of the bacterium Escherichia coli and the M26 site of the ...
openaire   +3 more sources

Homologous recombination in plants

Experientia, 1994
In plants three different approaches have been used to study homologous DNA recombination; extrachromosomal recombination (ECR) between transfected DNA molecules, intrachromosomal recombination (ICR) between repeated genes integrated into and resident at the genome and recombination between introduced DNA and homologous sequences in the genome (gene ...
Puchta, H., Swoboda, P., Hohn, B.
openaire   +3 more sources

Mechanism of Eukaryotic Homologous Recombination

Annual Review of Biochemistry, 2008
Homologous recombination (HR) serves to eliminate deleterious lesions, such as double-stranded breaks and interstrand crosslinks, from chromosomes. HR is also critical for the preservation of replication forks, for telomere maintenance, and chromosome segregation in meiosis I.
Hannah L. Klein, Patrick Sung, Joseph San Filippo   +2 more
openaire   +3 more sources