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Altering the Genome by Homologous Recombination [PDF]

Science, 1989
Homologous recombination between DNA sequences residing in the chromosome and newly introduced, cloned DNA sequences (gene targeting) allows the transfer of any modification of the cloned gene into the genome of a living cell. This article discusses the current status of gene targeting with particular emphasis on germ line modification of the mouse ...
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Homologous Recombination: A ring for a warhead

Current Biology, 1994
The active 'warhead' RuvB of the Escherichia coli protein that catalyzes the branch-migration step of homologous recombination is a helicase that binds DNA as a double-ring oligomer.
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The cell biology of homologous recombination

2006
Discontinuities in double-stranded DNA, such as DNA double-strand breaks (DSBs), pose a threat to genome stability. Homologous recombination is a process that not only effectively repairs DSBs, but also promotes preservation of genome integrity by repairing DNA discontinuities arising during DNA replication.
Roland Kanaar, Jeroen Essers, Sheba Agarwal   +2 more
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Homologous recombination

Experientia, 1994
W D, Heyer, J, Kohli
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Recombination Hotspots in Nonallelic Homologous Recombination

2007
Rearrangement breakpoints resulting from nonallelic homologous recombination (NAHR) are typically clustered within small, well-defined portions of the segmental duplications that promote the rearrangement. These NAHR “hotspots” have been identified in every NAHR-promoted rearrangement in which breakpoint junctions have been sequenced in sufficient ...
Matthew E. Hurles, James R. Lupski
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Recombination | Homologous Recombination in Meiosis

Encyclopedia of Biological Chemistry III, 2021
N. M. Hollingsworth, Hani S. Zaher
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Detecting the mutational signature of homologous recombination deficiency in clinical samples

Nature Genetics, 2019
D. Gulhan, J. Lee, G. Melloni, I. Cortés-Ciriano, P. Park   +4 more
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Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes

Chromosoma, 2018
Lepakshi Ranjha, S. Howard, Petr Cejka
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Homologous recombination v1

protocols.io, 2020
Linsheng Zhang
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Homologous Recombination Repair

2006
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