Results 1 to 10 of about 1,015,655 (285)

Twisted Homology [PDF]

open access: yesJournal of High Energy Physics, 2006
D-branes are classified by twisted K-theory. Yet twisted K-theory is often hard to calculate. We argue that, in the case of a compactification on a simply-connected six manifold, twisted K-theory is isomorphic to a much simpler object, twisted homology ...
Collinucci, Andres, Evslin, Jarah
core   +6 more sources

Natural variations in AAVHSC16 significantly reduce liver tropism and maintain broad distribution to periphery and CNS

open access: yesMolecular Therapy: Methods & Clinical Development, 2022
Adeno-associated viruses derived from human hematopoietic stem cells (AAVHSCs) are naturally occurring AAVs. Fifteen AAVHSCs have demonstrated broad biodistribution while displaying differences in transduction.
Laura J. Smith   +19 more
doaj   +1 more source

Homology of homologous knotted proteins

open access: yesJournal of The Royal Society Interface, 2023
Quantification and classification of protein structures, such as knotted proteins, often requires noise-free and complete data. Here, we develop a mathematical pipeline that systematically analyses protein structures. We showcase this geometric framework on proteins forming open-ended trefoil knots, and we demonstrate that the mathematical tool ...
Katherine Benjamin   +6 more
openaire   +6 more sources

DNA read count calibration for single-molecule, long-read sequencing

open access: yesScientific Reports, 2022
There are many applications in which quantitative information about DNA mixtures with different molecular lengths is important. Gene therapy vectors are much longer than can be sequenced individually via short-read NGS.
Luis M. M. Soares   +6 more
doaj   +1 more source

LNA blockers for improved amplification selectivity

open access: yesScientific Reports, 2023
LNA-containing oligonucleotides bind DNA more tightly than standard DNA, so they can interact with targeted sequences and affect multiple processes. When a desired DNA is present at low concentrations relative to nearly identical undesired DNAs, LNAs can
Jaime Prout   +4 more
doaj   +1 more source

Homological scaffold via minimal homology bases [PDF]

open access: yesScientific Reports, 2021
AbstractThe homological scaffold leverages persistent homology to construct a topologically sound summary of a weighted network. However, its crucial dependency on the choice of representative cycles hinders the ability to trace back global features onto individual network components, unless one provides a principled way to make such a choice.
Guerra, Marco   +4 more
openaire   +6 more sources

New insights into the origin and relationships of blastoid echinoderms [PDF]

open access: yesActa Palaeontologica Polonica, 2021
“Pan-dichoporites” (new informal term) is proposed to unite Cambrian blastozoans, such as Cambrocrinus, Ridersia, and Sanducystis, glyptocystitoid and hemicosmitoid rhombiferans, coronates, blastoids, and Lysocystites.
Christopher R.C. Paul
doaj   +1 more source

Sustained Correction of a Murine Model of Phenylketonuria following a Single Intravenous Administration of AAVHSC15-PAH

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Phenylketonuria is an inborn error of metabolism caused by loss of function of the liver-expressed enzyme phenylalanine hydroxylase and is characterized by elevated systemic phenylalanine levels that are neurotoxic.
Seemin S. Ahmed   +14 more
doaj   +1 more source

THE HOMOLOGY OF DIGRAPHS AS A GENERALIZATION OF HOCHSCHILD HOMOLOGY [PDF]

open access: yesJournal of Algebra and Its Applications, 2012
Przytycki has established a connection between the Hochschild homology of an algebra A and the chromatic graph homology of a polygon graph with coefficients in A. In general the chromatic graph homology is not defined in the case where the coefficient ring is a non-commutative algebra.
Turner Paul, Wagner Emmanuel
openaire   +4 more sources

Chemical Composition, Antibacterial, Anti-Inflammatory, and Enzyme Inhibitory Activities of Essential Oil from Rhynchanthus beesianus Rhizome

open access: yesMolecules, 2020
Rhynchanthus beesianus W. W. Smith, an edible, medicinal, and ornamental plant, is mainly cultivated in China and Myanmar. The essential oil (EO) from R. beesianus rhizome has been used as an aromatic stomachic in China.
Xiaoge Zhao   +7 more
doaj   +1 more source

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