Results 161 to 170 of about 660,490 (319)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Boundaries, spectral triples and K-homology [PDF]
, 2019 This paper extends the notion of a spectral triple to a relative spectral triple, an unbounded analogue of a relative Fredholm module for an ideal J◃A.
Iain Forsyth (20118510) +3 more
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Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
DIVIDED POWER (CO)HOMOLOGY. PRESENTATIONS OF SIMPLE FINITE DIMENSIONAL MODULAR LIE SUPERALGEBRAS WITH CARTAN MATRIX [PDF]
, 2010 For modular Lie superalgebras, new notions are introduced: Divided power homology and divided power cohomology. For illustration, we explicitly give presentations (in terms of analogs of Chevalley generators) of finite dimensional Lie (super) algebras ...
Grozman, Pavel +3 more
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Editorial: Teleostean forebrain organization and evolution: Links to behavior and ecological niche
Frontiers in Neuroanatomy, 2023 Mónica Folgueira +2 more
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Stratifying Multiparameter persistent homology (joint work with H. Harrington, N. Otter, U.Tillmann). [PDF]
, 2019 A fundamental tool in topological data analysis is persistent homology, which allows extraction of information from complex datasets in a robust way. Persistent homology assigns a module over a principal ideal domain to a one-parameter family of spaces ...
Schenck, Hal
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