Results 221 to 230 of about 305,462 (309)

The eukaryotic homology search complex distorts donor DNA structure to probe for homology. [PDF]

Genes Dev
Woodhouse MV, Hu J, Wu M, Qian J, Inman JT, Wang MD, Crickard JB.   +6 more
europepmc   +1 more source

On central group extensions and homology

Commentarii Mathematici Helvetici, 1971
ECKMANN, B., HILTON, P.J.
openaire   +2 more sources

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Low temperature rather than hypoxia drives cholesterol synthesis and oxygen consumption in plateau zokors. [PDF]

iScience
Hu Q, Wei L, An Z, Wang Y, Zhang T, Wei D.   +5 more
europepmc   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Pants Homology for Surfaces [PDF]

, 2013
Marzioni, Simone
core  

Expression of a phage RecET recombinase system improves detection of shorter DNA fragments by an <i>Acinetobacter baylyi</i> ADP-ISx antibiotic gene biosensor strain. [PDF]

MicroPubl Biol
Rhyan N, Koshy IS, Dinh R, VanDieren AJ, Mishler DM, Barrick JE.   +5 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Deligne homology, Hodge-D-conjecture, and motives [PDF]

, 1988
Jannsen, Uwe
core  

quercusTOA: integrating functional annotations and comparative genomics across oak lineages. [PDF]

Front Bioinform
Mora-Márquez F, Hurtado M, López de Heredia U.   +2 more
europepmc   +1 more source