Results 261 to 270 of about 58,203 (304)
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Homozygosity in three-allele populations
Theoretical Population Biology, 1978Abstract Testing the null hypothesis that mutations are selectively neutral can be carried out using the observed homozygosity (the sum of squares of the allele frequencies). Assuming that the population is statistically stationary and practices random mating, its homozygosity has a probability distribution under the null hypothesis which is free of ...
Watterson, G. A., Perlow, J.
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Homozygosity of Chromosome 13 in Retinoblastoma
New England Journal of Medicine, 1984We studied the frequency of chromosome 13 homozygosity in tumor tissue obtained directly from eyes harboring retinoblastomas. The data indicate that approximately half of all retinoblastomas are homozygous for large portions of 13q, that the homozygosity occurs in vivo and not as an event secondary to culture of the tumor cells, that chromosome 13 ...
T P, Dryja +6 more
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Homozygosity and S Gene Mutation
Nature, 1959THE S locus governing gametophytic self-incompatibility in plants is particularly suited to mutation studies. Pollen grains having an unmutated allele are unable to grow through a style carrying the same allele. In contrast ‘mutant’ grains produce pollen-tubes which may overcome the incompatibility barrier.
J L, BREWBAKER, N, SHAPIRO
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Dominance and homozygosity in man
American Journal of Medical Genetics, 1983Reflexion selon laquelle la dominance complete n'existe probablement pas dans les maladies genetiques humaines et illustree par un tableau de 11 maladies dominantes a ...
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Hypothesis: Homozygosity in tourette syndrome
American Journal of Medical Genetics, 1989AbstractWe review evidence suggesting that many individuals with Tourette syndrome (TS) may be homozygous for a “Tourette syndrome” gene. This is based on experience with pedigrees on 1,200 TS families, comparison of the occurrence of tics or associated behaviors such as obsessive‐compulsive behavior, panic attacks, attention deficit hyperactivity ...
D E, Comings, B G, Comings, E, Knell
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Homozygosity for inversion (2)(p12q14)
Human Genetics, 1993Two healthy adults, brother and sister, who are homozygotes for inv2(p12q14) are reported. As this is the first report of homozygosity for this inversion the authors ask to be informed of any further known cases.
Z, Gelman-Kohan +3 more
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Homozygosity for Hemochromatosis: Clinical Manifestations
Annals of Internal Medicine, 1980We identified 35 homozygotes for hemochromatosis through pedigree studies. Thirteen were asymptomatic. Arthropathy was present in 20, hepatomegaly in 19, transaminasemia in 16, skin pigmentation in 15, splenomegaly in 14, cirrhosis in 14, hypogonadism in six, and diabetes in two. No homozygote was in congestive failure.
C Q, Edwards +3 more
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Homozygosity for uromodulin disorders: FJHN and MCKD-type 2
Kidney International, 2004MIGUEL A Garcia-Gonzalez
exaly