Results 131 to 140 of about 43,378 (245)

Contributions of selenoproteins to breast cancer etiology and racial disparity. [PDF]

Cancer Causes Control
Bera S, Liu L, Ma W, Xu Z, Sverdlov M, Deaton R, Macias V, Valyi-Nagy K, Kajdacsy-Balla A, Hoskins K, Wiley EL, Kastrati I, Diamond AM.   +12 more
europepmc   +1 more source

Cytokine Gene Variants Are Associated With Aerobic Fitness‐Related, Hematological, and Metabolic Traits in Healthy Adults

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Analysis of ~1000 adults shows cytokine gene variants are more strongly associated with hematological and metabolic traits than fitness classification. IL6 and TNF‐α variants link to iron status and aerobic fitness, with exploratory multi‐locus effects involving IL15. ABSTRACT Genetic variation in cytokine genes may influence cytokine‐related signaling,
Kinga Humińska‐Lisowska, Barkın Bıçakçı, Monika Michałowska‐Sawczyn, Piotr Aschenbrenner, Alison V. September, Patrizia Proia, Agata Leońska‐Duniec   +6 more
wiley   +1 more source

Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case-Control Study. [PDF]

J Clin Lab Anal
Islam JMA, Ahamed S, Islam S, Hossain MM, Hossain MS, Mostaid MS, Islam MR, Haque MA.   +7 more
europepmc   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 510-519, August 2026.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

The <i>grooveless</i> gene encodes a single von Willebrand factor type C domain protein necessary for proper formation of the scutoscutellar sulcus in <i>Drosophila melanogaster</i>. [PDF]

MicroPubl Biol
Cook KR, Mauthner SE.
europepmc   +1 more source

Germline predisposition and somatic mutational landscape in synchronous mucinous metaplasia and neoplasia of the female genital tract

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN‐FGT) is characterised by an enrichment of pathogenic germline variants in cancer‐predisposition genes, particularly BRCA1 and other homologous recombination repair genes. Recurrent TP53 mutations are concentrated in malignant lesions, while clonal and functional analyses ...
Ying Yuan, Li Zhang, Jiongbo Liao, Bo Wang, Linghui Lu, Dongchen Chu, Yue Shi, Jiaqi Liu, Feng Zhang, Shuyan Tang, Chao Wang   +10 more
wiley   +1 more source

Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities. [PDF]

Hum Genet
Durodoye RO, Ciesielski TH, Benchek P, Bartlett J, Zhu X, Liu S, Naj A, Kunkle B, Schellenberg GD, Mayeux R, Farrer L, Wang LS, Pericak-Vance MA, Rajabli F, Tosto G, Haines JL, Bush WS, Williams SM.   +17 more
europepmc   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, Volume 255, Issue 8, Page 808-823, August 2026.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

The Role of Pyridoxine Treatment for Seizures in Patients with PGAP3-Congenital Disorders of Glycosylation. [PDF]

Ann Indian Acad Neurol
Beşen Ş, Özkale Y, Sangün Ö, Erol İ.   +3 more
europepmc   +1 more source

Evaluation of The Use of Hydroxyurea in Treating Children With Sickle Cell Anemia in Central Africa's Rural Area

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Sickle cell anemia (SCA) is highly prevalent in Central Africa. This disease causes severe manifestations in children, requiring treatment. Hydroxyurea (HU) is currently the most effective treatment for SCA. We evaluated the use of HU in children living in rural Central Africa.
Gloire Mbayabo, Paul Lumbala Kabuyi, Mamy Ngole, Aimé Lumaka, Valerie Race, Gert Matthijs, Tite Mikobi Minga, Koenraad Devriendt, Chris Van Geet, Prosper Tshilobo Lukusa   +9 more
wiley   +1 more source