Results 11 to 20 of about 73,318 (285)

Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector Anopheles funestus but PBO-Based Olyset Plus Net Remains Effective

Pathogens, 2022
Malaria remains a major public health concern in Africa. Metabolic resistance in major malaria vectors such as An. funestus is jeopardizing the effectiveness of long-lasting insecticidal nets (LLINs) to control malaria.
Benjamin D. Menze, Leon M. J. Mugenzi, Magellan Tchouakui, Murielle J. Wondji, Micareme Tchoupo, Charles S. Wondji   +5 more
doaj   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

A novel Gly436Glu variant in the LPL gene identified in a Saudi Arabian patient with severe hypertriglyceridemia and recurrent pancreatitis [PDF]

Precision and Future Medicine
Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disorder characterized by severe hypertriglyceridemia and recurrent pancreatitis, often manifesting in childhood.
Dena A. Nuwaylati, Hussam Daghistani, Noor Ahmad Shaik, Zuhier A. Awan   +3 more
doaj   +1 more source

Combinations of genetic variants associated with bipolar disorder. [PDF]

PLoS ONE, 2017
The main objective of the study was to find genetic variants that in combination are significantly associated with bipolar disorder. In previous studies of bipolar disorder, combinations of three and four single nucleotide polymorphisms (SNP) genotypes ...
Erling Mellerup, Ole A Andreassen, Bente Bennike, Henrik Dam, Srdjan Djurovic, Martin Balslev Jorgensen, Lars Vedel Kessing, Pernille Koefoed, Ingrid Melle, Ole Mors, Gert Lykke Moeller   +10 more
doaj   +1 more source

Evaluation of the Role of the KRAS Gene Polymorphism LCS6 (rs61764370) in Iraqi Women with Ovarian Cancer [PDF]

Archives of Razi Institute, 2022
In carcinogenesis, KRAS is an essential oncogene that plays a key function. The polymorphism of rs61764370 is a candidate for cancer susceptibility in KRAS3' untranslated region.
M Ghazi Jumaa
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

A Case of Cerebral Amyloid Angiopathy-Related Inflammation With the Rare Apolipoprotein ε2/ε2 Genotype

Frontiers in Neurology, 2019
Cerebral amyloid angiopathy (CAA)-related inflammation (CAA-RI) is a rare CAA variant characterized by acute or subacute encephalopathy, headache, epilepsy, or focal neurological deficits.
Yin-Yan Xu, Shuai Chen, Jian-Hua Zhao, Xi-Ling Chen, Jie-Wen Zhang   +4 more
doaj   +1 more source

Genetic Diversity Analysis of Mulberry Silkworm (Bombyx Mori L.) Hybrids and Breeds in Azerbaijan Using RAPD Markers [PDF]

BIO Web of Conferences
In order to study the genetic diversity of silkworms (Bombyx mori L.) breeding in Azerbaijan, the following breeds and hybrids were analyzed: SHZEM 4 x GE 143, Chingiz x Yagub, Yagub x Chingiz, GE 143, Yagub, SHZEM 4 belted, Chingiz, GE 143 x SHZEM 4 ...
Mammadov Ayaz, Aghayeva Saltanat, Bakırov Guduret, Gulubeyova Mahpuba, Ismayılova Gular   +4 more
doaj   +1 more source

Association study between BGLAP RS1800247-polymorphic variant and type 2 diabetes mellitus development among hypertensive and non-hypertensive Ukrainians

Zaporožskij Medicinskij Žurnal, 2021
The risk of type 2 diabetes mellitus (T2DM) development depends on a hereditary predisposition. According to the current data, bone tissue enhances insulin gene expression in pancreatic β-cells as well as increases insulin sensitivity of adipocytes ...
Ya. D. Chumachenko, M. O. Kyrychenko, D. M. Ramazanova, M. V. Smiianova, V. Yu. Harbuzova, O. V. Ataman   +5 more
doaj   +1 more source

Vascular Calcifications in Homozygote Familial Hypercholesterolemia [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008
Background— Patients with homozygous familial hypercholesterolemia (hmzFH) attributable to LDL receptor gene mutations have shown a remarkable increase in survival over the last 20 years. Early onset coronary heart disease (CHD) and calcific aortic valve stenosis are the major complications of this ...
Z, Awan, K, Alrasadi, G A, Francis, R A, Hegele, R, McPherson, J, Frohlich, D, Valenti, B, de Varennes, M, Marcil, C, Gagne, J, Genest, P, Couture   +11 more
openaire   +2 more sources