Results 21 to 30 of about 73,318 (285)

Gene dynamics of toll-like receptor 4 through a population bottleneck in an insular population of water voles (Arvicola amphibius) [PDF]

, 2015
Acknowledgments We would like to thank all colleagues who have contributed to fieldwork and sampling during this study. We would especially like to thank Marius Wenzel and Sandra Telfer for collaboration with different aspects of the study, and Dave ...
Douglas, Alex, Gavan, Martha K., Oliver, Matthew K., Piertney, Stuart B.   +3 more
core   +2 more sources

Effect of the Point Mutation in Growth Differentiation Factor 9 Gene in Awassi Sheep Oocytes on Sterility and Fertility

Journal of Pure and Applied Microbiology, 2018
Growth differentiation factor 9 (GDF9) is play a critical role in ovarian follicular development and ovulation rate. The present research was performed to investigate the correlation between single nucleotide polymorphism (SNP) of GDF9 gene and ...
H. Al-Mutar, L. Younis, H. Khawla
doaj   +1 more source

EPHX1 and GSTP1 polymorphisms are associated with COPD risk: a systematic review and meta-analysis

Frontiers in Genetics, 2023
Background: Chronic obstructive pulmonary disease (COPD) affects approximately 400 million people worldwide and is associated with high mortality and morbidity.
Qinjun Yang, Qinjun Yang, Qinjun Yang, Wanqiu Huang, Dandan Yin, Lu Zhang, Yating Gao, Jiabing Tong, Jiabing Tong, Jiabing Tong, Zegeng Li, Zegeng Li, Zegeng Li   +12 more
doaj   +1 more source

Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects

Journal of Lipid Research, 2000
We measured the percent absorption, turnover, and distribution of campestanol (24-methyl-5α-cholestan-3β-ol) in a sitosterolemic homozygote, her obligate heterozygous mother, and three healthy human control subjects.
Gerald Salen, Guorong Xu, G.S. Tint, A.K. Batta, Sarah Shefer   +4 more
doaj   +1 more source

Genetic polymorphism of ALDH2 in Indonesia’s Minang ethnic

Acta Biochimica Indonesiana, 2021
Background: In some people, acetaldehyde, a toxic product from ethanol oxidation, cannot be oxidized to acetate. The excess of acetaldehyde could cause facial flushing, dizziness, and hypertension when they consume ethanol.
Abdul Halim Sadikin, Irene Dian, Mukharjon Mukharjon, Rini Puspitaningtum, Septelia Inawati Wanandi   +4 more
doaj   +1 more source

Narrative role of vitamin D receptor with osteoporosis and obesity in a sample of Egyptian females: a pilot study

Journal of Genetic Engineering and Biotechnology, 2021
Background Vitamin D receptor (VDR) is known as one of the cellular regulators for several metabolic pathways indicating its pivotal role in the pathological pathway of numerous diseases.
Nayera E. Hassan, Sahar A. El-Masry, Waheba Ahmed Zarouk, Ghada Nour Eldeen, Rehab M. Mosaad, Mahmoud A. S. Afify, Manal M. Aly, Aya Khalil   +7 more
doaj   +1 more source

Variations in GLP-1R rs2268641 increase risk of diabetic nephropathy in China [PDF]

Jichu yixue yu linchuang
Objective To investigate the association between glucagon-like peptide-1 receptor (GLP-1R) gene polymorphism (rs2268641) and the incidence of diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM). Methods A total of 490 T2DM patients
HE Ke, YANG Fan, LU Xiwan, HU Yun
doaj   +1 more source

The Role of Dopamine in Anticipatory Pursuit Eye Movements: Insights from Genetic Polymorphisms in Healthy Adults [PDF]

, 2016
There is a long history of eye movement research in patients with psychiatric diseases for which dysfunctions of neurotransmission are considered to be the major pathologic mechanism.
Billino, Jutta, Gegenfurtner, Karl R., Hennig, Jürgen   +2 more
core   +1 more source

Under-dominance constrains the evolution of negative autoregulation in diploids [PDF]

, 2012
Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change.
Pomiankowski, Andrew, Reuter, Max, Seymour, Robert M., Stewart, Alexander J.   +3 more
core   +8 more sources

First Steps towards Underdominant Genetic Transformation of Insect Populations [PDF]

, 2014
The idea of introducing genetic modifications into wild populations of insects to stop them from spreading diseases is more than 40 years old. Synthetic disease refractory genes have been successfully generated for mosquito vectors of dengue fever and ...
AG Clark, AH Brand, Alexander W. E. Franz, AT Isaacs, AWE Franz, C Curtis, CH Chen, CL Holley, D-U Kim, E Enerly, Floyd A. Reed, J Bischof, Jai A. Denton, Jarosław Bryk, JB Duffy, JM Marshall, K Ito, K Williams, LB Weinstein, M Ràmia, N Barton, N Jasinskiene, N Windbichler, Philipp M. Altrock, PM Altrock, PM Altrock, R. Guy Reeves, RD Seager, RK Cook, S Cherry, S Davis, S Saebøe-Larssen, S Wilks, S Wright, SJ Marygold, SJ Marygold, SP Sinkins, SS Wilks, T Nolan, TW Scott, V Kokoza, VR Chintapalli, Y Dong   +42 more
core   +4 more sources