Results 31 to 40 of about 73,318 (285)

Association between the insulin-like growth factor 1 gene rs2195239 and rs2162679 polymorphisms and cancer risk: a meta-analysis

BMC Medical Genetics, 2019
Background Many epidemiological studies have suggested that insulin-like growth factor1 (IGF1) gene single-nucleotide polymorphisms (SNPs) may be associated with cancer risk.
Gui-Ping Xu, Wei-Xian Chen, Qing Zhao, Hua Zhou, Shi-Zhi Chen, Li-Fang Wu   +5 more
doaj   +1 more source

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia [PDF]

, 2014
© The Author 2014. Published by Oxford University Press This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution,
Al-Mahdawi, Al-Mahdawi, Block, Campuzano, Campuzano, Capdevila, Capdevila, Castaldo, Chantrel-Groussard, Chen, Cossee, Dewitt, Durr, Durr, Feng, Genki Hayashi, Gino Cortopassi, Harding, John W. Newman, Kang, Koeppen, Li, Liang, Lin, Lu, Mark Pook, Masi, Michael, Miranda, Node, O'Flaherty, Paupe, Piemonte, Piro, Praticò, Qin, Ristow, Rojo, Samuelsson, Sanchez-Mejia, Schulz, Shan, Shi, Shin, Small, Smith, Strokin, Tan, Teismann, Theresa L. Pedersen, Tian, Wardlaw, Wong, Wong, Xi, Yan, Yan Shen, Zhang   +57 more
core   +2 more sources

Vitamin D receptor gene polymorphisms on the risk of tuberculosis, a meta-analysis of 29 case-control studies. [PDF]

PLoS ONE, 2013
The relationship of four potentially functional polymorphisms of the vitamin D receptor (VDR) gene, ApaI, BsmI, FokI and TaqI , with tuberculosis susceptibility were considered.
Cheng Chen, Qiao Liu, Limei Zhu, Haitao Yang, Wei Lu   +4 more
doaj   +1 more source

Genetic polymorphisms in CYP4F2 may be associated with lung cancer risk among females and no-smoking Chinese population

Frontiers in Oncology, 2023
BackgroundOur study aimed to explore the potential association of CYP4F2 gene polymorphisms with lung cancer (LC) risk.MethodsThe five variants in CYP4F2 were genotyped using Agena MassARRAY in 507 cases and 505 controls.
Hongyang Shi, Yonghong Zhang, Yu Wang, Ping Fang, Yun Liu   +4 more
doaj   +1 more source

A framework for gene mapping in wheat demonstrated using the Yr7 yellow rust resistance gene [PDF]

, 2020
We used three approaches to map the yellow rust resistance gene Yr7 and identify associated SNPs in wheat. First, we used a traditional QTL mapping approach using a double haploid (DH) population and mapped Yr7 to a low-recombination region of chromosome
Bansept-Basler, Pauline, El-Soda, Mohamed, Gardiner, Laura-Jayne, Hall, Anthony, O'Sullivan, Donal M.   +4 more
core   +3 more sources

Homozygote Depression in Gamete-Derived Dragon-Fruit (Hylocereus) Lines

Frontiers in Plant Science, 2018
Putative gamete-derived progenies from two Hylocereus species, the diploid H. monacanthus and the tetraploid H. megalanthus, were studied with the dual aims to confirm their gamete origin and to evaluate their potential use as genetic resources.
Daqing Li, Daqing Li, Maria F. Arroyave Martinez, Ruth Shaked, Noemi Tel-Zur   +4 more
doaj   +1 more source

Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. [PDF]

, 2019
We identified a PSEN1 (presenilin 1) mutation carrier from the world's largest autosomal dominant Alzheimer's disease kindred, who did not develop mild cognitive impairment until her seventies, three decades after the expected age of clinical onset.
A Butler, A Lalazar, A Llado, Aaron P. Schultz, Ana Baena, Arabiye Artola, AS Fleisher, Claudia Marino, D Smedley, Daniel J. Norton, David Aguillon, David Leyton-Cifuentes, DC Aguirre-Acevedo, Dhanesh Amarnani, DM Walsh, DT Chien, E Hudry, EC Mormino, Edmarie Guzmán-Vélez, EH Corder, Enmanuelle Pardilla-Delgado, Eric M. Reiman, Francisco Lopera, Gyungah R. Jun, H Braak, H Braak, Henrik Zetterberg, J Logan, JA Becker, Ji Luo, JI Velez, Jianling Ji, JN Rauch, John B. Miller, Joseph F. Arboleda-Velasquez, Juliana Acosta-Uribe, Justin S. Sanchez, KA Johnson, Kahira L. Saez-Torres, Kaj Blennow, Keith A. Johnson, Kenneth S. Kosik, Kewei Chen, L Wang, L Zhong, Leo A. Kim, Lishuang Shen, M Futamura, M Gisslén, MA Lalli, Marcus Naymik, Margarita Giraldo, Matthew J. Huentelman, Matthew Lalli, Michael O’Hare, Moiz Bootwalla, MR Wardell, N Acosta-Baena, Natalia Chmielewska, O Preische, Pierre N. Tariot, Pradeep Thiyyagura, Rebecca A. Reiman, Reisa A. Sperling, RW Mahley, S Fisher, S Thordardottir, Santiago Delgado-Tirado, Silvia Rios-Romenets, T Hashimoto, T Hashimoto, T Hedden, TM Shoup, WD Knight, Xiaowu Gai, Y Yamauchi, Yakeel T. Quiroz, Yi Su, Yinghua Chen, YT Quiroz   +79 more
core   +3 more sources

Interethnic diversity of the CD209 (rs4804803) gene promoter polymorphism in African but not American sickle cell disease [PDF]

PeerJ, 2015
Elucidating the genomic diversity of CD209 gene promoter polymorphism could assist in clarifying disease pathophysiology as well as contribution to co-morbidities.
Jenelle A. Noble, Kimberley C. Duru, Aldiouma Guindo, Li Yi, Ikhide G. Imumorin, Dapa A. Diallo, Bolaji N. Thomas   +6 more
doaj   +2 more sources

The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens

Journal of Integrative Agriculture, 2012
Variants in chicken growth hormone receptor (GHR) gene lead to sex-linked dwarf (SLD) chickens, but effects of different variants are distinct. In this study, 11 SLD chicken breeds or strains including 3 Chinese native breeds and 8 breeding strains were ...
Jian-hua OUYANG, Liang XIE, Qing-hua NIE, Hua ZENG, Zhi-jun PENG, De-xiang ZHANG, Xi-quan ZHANG   +6 more
doaj   +1 more source

Under-dominance constrains the evolution of negative autoregulation in diploids [PDF]

, 2013
Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change.
Pomiankowski, A, Reuter, M, Seymour, RM, Stewart, AJ   +3 more
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