The roles of ACE I/D and ACTN3 R577X gene variants in heat acclimation
HeliyonRoles of genes in heat acclimation (HA, repeated exercise-heat exposures) had not been explored. ACE I/D and ACTN3 R577X genetic polymorphisms are closely associated with outstanding exercise performances.
Tao Liu
doaj +1 more source
Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity [PDF]
, 1995 Strong's Luxoid (1st^D) is a semidominant mouse mutation in which heterozygotes show preaxial hindlimb polydactyly, and homozygotes show fore- and hindlimb polydactyly.
Chan, David C. +3 more
core
Association of interleukin 10 rs1800896 polymorphism with susceptibility to breast cancer: a meta-analysis. [PDF]
, 2020 Objective: To evaluate the correlation between interleukin 10 (IL-10) -1082A/G polymorphism (rs1800896) and breast cancers by performing a meta-analysis.
Liu, Ji-Bin +3 more
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APOE genotype and the effect of statins on lipid outcomes: A meta‐analysis
British Journal of Clinical Pharmacology, EarlyView.Aim APOE genotype may affect statin therapy response. We conducted a meta‐analysis to update and quantify this association across various outcomes. Methods We searched seven databases (MEDLINE, Scopus, Web of Science, the Cochrane Library, APA PsycINFO, CINAHL Plus and ClinicalTrials.gov) on 9 May 2024.
Innocent G. Asiimwe +4 more
wiley +1 more source
BMC Gastroenterology, 2013 Background Aberrant methylation patterns in CpG island are known to be influential in gene silencing. Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor.
Nomura Tomoe +11 more
doaj +1 more source
Establishment of Homozygote Mutant Human Embryonic Stem Cells by Parthenogenesis. [PDF]
PLoS ONE, 2015 We report on the derivation of a diploid 46(XX) human embryonic stem cell (HESC) line that is homozygous for the common deletion associated with Spinal muscular atrophy type 1 (SMA) from a pathenogenetic embryo.
Silvina Epsztejn-Litman +9 more
doaj +1 more source
Animals, 2023 Sex-linked phenotypes of late feathering (LF) and early feathering (EF) are controlled by a pair of alleles K and k+. Autosexing based on the feathering rate is widely used in poultry production.
Qingmiao Shen +3 more
doaj +1 more source
Natural History of C282Y Homozygotes for Hemochromatosis [PDF]
Canadian Journal of Gastroenterology, 2002 PURPOSE: To study the clinical outcomes of subjects who are homozygous for the C282Y mutation of the hemochromatosis gene.SUBJECTS AND METHODS: All patients referred to a tertiary referral centre for hemochromatosis were included. The study also included 16 C282Y homozygotes detected in a population screening study.RESULTS: The study comprised 277 ...
John P Wojcik +4 more
openaire +3 more sources
Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian [PDF]
, 2009 Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Fuhou Chang +6 more
core +1 more source
Invited review: Bioinformatic methods to discover the likely causal variant of a new autosomal recessive genetic condition using genome-wide data [PDF]
, 2018 In animals, new autosomal recessive genetic diseases (ARGD) arise all the time due to the regular, random mutations that occur during meiosis. In order to reduce the effect of any damaging new variant, it is necessary to find its cause.
Pollott, G E
core +2 more sources