Results 211 to 220 of about 1,359,492 (341)

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

UNICORN for Valve-in-Valve Transcatheter Aortic Valve Replacement: UNICORN Hong Kong Registry. [PDF]

JACC Asia
Wong CK, Eric Chan KY, Chan DT, Chiu HAC, Un KC, Sze SY, Tam FC, Lee CW, Wong MK, Lau M, Law PK, Ko AT, Shek J, Lam TH, Lee YT, Cheng MK, Lin M, Lam YM, Tang GHL, Lam SC.   +19 more
europepmc   +1 more source

Mobile phone surveys in Hong Kong : methodological issues and comparisons with conventional phone surveys

, 2005
Ka-po Lau
openalex   +1 more source

Electron‐Mediator‐Free Microfluidic Photocatalytic Coenzyme Regeneration with 100% Conversion Efficiency within 126 S

Advanced Science, EarlyView.
Discover a groundbreaking mediator‐free photocatalytic method for coenzyme NAD(P)H regeneration using BiOBr nanosheets in a microfluidic chip. This study achieves 100% NAD+ to NADH conversion in 126 s, maintaining >87% efficiency over 32 h. Explore how photocatalysis and microfluidics combine to offer a sustainable, scalable solution for green ...
Yao Chai, Liang Wan, Zirui Pang, Xu Li, Zixuan Jia, Heng Jiang, Chi Chung Tsoi, Huaping Jia, Jinni Shen, Zizhong Zhang, Jinlin Long, Fengjia Xie, Yanmei Chen, Xuming Zhang   +13 more
wiley   +1 more source

Seasonal Influenza Vaccination Uptake and Intentions Among Nursing Students in Hong Kong. [PDF]

Vaccines (Basel)
Hung MSY, Wan GSK, Chua WH, Cheng CM.
europepmc   +1 more source

Initial Distance‐Dependent Mean Force Drives Synaptic Vesicle Motion Toward Fusion Sites in Stimulated Hippocampal Neurons

Advanced Science, EarlyView.
Synaptic vesicle (SV) motion and exocytosis dynamics in the presynaptic terminals of live neurons are intimately linked to synaptic transmission during neuronal activity. In this work, it is revealed that, during electrical stimulation, SVs located farther from their fusion sites exhibit greater straightness and experience larger mean forces directed ...
Gyunam Park, Ji‐Hyun Kim, Hunki Lee, Chungwon Park, Sidong Chen, Luke Bates, Jaeyoung Sung, Hyokeun Park   +7 more
wiley   +1 more source

Remade in Hong Kong : how Hong Kong people use Hong Kong Disneyland

, 2014
openaire   +2 more sources

POLICE CORRUPTION CONTROL IN HONG KONG AND NEW YORK CITY:A Dilemma of Checks and Balances in Combating Corruption

, 2008
jinhua cheng
openalex   +1 more source

Hong Kong Government criteria for assessing contamination levels of dredged marine sediments

, 2000
James Kit-cheong
openalex   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

Advanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao, Guiyuan Shi, Ruixue Qin, Yinghao Sun, Wenbo Guo, Ruixia Shi, Minxian Peng, Jingxuan Yang, Jianjian Zhao, Qiuhan Liu, Jun Xiao, Ke Zhang, Qiang Liu, Wenxing Yang, He Liu   +14 more
wiley   +1 more source