Results 51 to 60 of about 51,386 (281)

Controlled infection with cryopreserved human hookworm induces CTLA-4 expression on Tregs and upregulates tryptophan metabolism

Gut Microbes
Infecting humans with controlled doses of helminths, such as human hookworm (termed hookworm therapy), is proposed to prevent or treat various intestinal and extraintestinal diseases.
Francesco Vacca, Thomas C. Mules, Mali Camberis, Brittany Lavender, Sophia-Louise Noble, Alissa Cait, Kate Maclean, John Mamum, Bibek Yumnam, Tama Te Kawa, Laura Ferrer-Font, Jeffry S. Tang, Olivier Gasser, Graham Le Gros, Stephen Inns   +14 more
doaj   +1 more source

Risk Factors for Anaemia Among HIV Infected Children Attending Care and Treatment Clinic at Muhimbili National Hospital in Dar es Salaam, Tanzania [PDF]

, 2012
There is paucity of data describing the risk factors for anaemia among HIV infected children in Tanzania. This cross sectional study was carried out to determine the contributing factors for anaemia among HIV-infected children attending Muhimbili ...
Magesa, Pius M., Makubi, Abel N., Mugusi, Ferdinand, Roberts, David   +3 more
core   +2 more sources

Detection of enteric parasite DNA in household and bed dust samples: potential for infection transmission. [PDF]

, 2020
BACKGROUND: Enteric parasites are transmitted in households but few studies have sampled inside households for parasites and none have used sensitive molecular methods.
Calderón, E, Cooper, PJ, Garcia-Ramon, D, Lopez, A, Mejia, R, Seco-Hidalgo, V   +5 more
core   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Else KJ, Garcia FT, McSharry C, Nakajima H, Oku Y, Pawlowski Z, Petit‐Frere C, Robinson K, Tilney LG, Urban JF, WHO, WHO   +11 more
core   +4 more sources

Gastroscopic diagnosis of ankylostoma duodenale infestation as a cause of iron-deficiency anemia

Medical Journal of Dr. D.Y. Patil University, 2014
Hookworm is one of the most common nematode causing intestinal infestation in the world. Patients with a mild hookworm load are usually asymptomatic, but a moderate or heavy hookworm burden can result in fatigue, recurrent abdominal pain and iron ...
Sunita Bamanikar, Arvind Bamanikar, Vinay Sawlani, Dakshayani Pandit   +3 more
doaj   +1 more source

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes

Infection and Immunity, 2019
Iatrogenic hookworm therapy shows promise for treating disorders that result from a dysregulated immune system, including inflammatory bowel disease (IBD).
P. Wangchuk, Catherine Shepherd, C. Constantinoiu, R. Ryan, K. Kouremenos, Luke Becker, L. Jones, G. Buitrago, P. Giacomin, David T. Wilson, N. Daly, M. McConville, John J Miles, A. Loukas   +13 more
semanticscholar   +1 more source

Effects of Video‐Based Health Education on Birth Outcomes and Anaemia Status of Mothers in Dirashe District South Ethiopia: A Cluster Randomized Controlled Trial

Maternal &Child Nutrition, EarlyView.
ABSTRACT Undernutrition and infections during pregnancy result in low birth weight (LBW) and maternal anaemia. Social behaviour change communication (SBCC) can promote recommended health practices, potentially improving maternal and neonatal outcomes.
Wanzahun Godana Boynito, Kidus Temesgen Worsa, Befikadu Tariku Gutema, Yordanos Gizachew Yeshitila, Godana Yaya Tessema, Tsegaye Yohanis, Stefaan De Henauw, Piet Cools, Bruno Levecke, Souheila Abbeddou   +9 more
wiley   +1 more source

Levels of serum eosinophil cationic protein are associated with hookworm infection and intensity in endemic communities in Ghana.

PLoS ONE, 2019
BackgroundThe eosinophil cationic protein (ECP) is a cytotoxic protein mainly secreted by eosinophils granulocytes and plays a role in host defense against parasitic infections.
Benjamin Amoani, Bright Adu, Margaret T Frempong, Tracy Sarkodie-Addo, Samuel Victor Nuvor, Michael D Wilson, Ben Gyan   +6 more
doaj   +1 more source

Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection. [PDF]

PLoS ONE, 2011
We present immunological data from two clinical trials where the effect of experimental human hookworm (Necator americanus) infection on the pathology of celiac disease was evaluated. We found that basal production of Interferon- (IFN-)γ and Interleukin-
Henry J McSorley, Soraya Gaze, James Daveson, Dianne Jones, Robert P Anderson, Andrew Clouston, Nathalie E Ruyssers, Richard Speare, James S McCarthy, Christian R Engwerda, John Croese, Alex Loukas   +11 more
doaj   +1 more source

Estimating sensitivity of the Kato-Katz technique for the diagnosis of Schistosoma mansoni and hookworm in relation to infection intensity

PLoS Neglected Tropical Diseases, 2017
The Kato-Katz technique is the most widely used diagnostic method in epidemiologic surveys and drug efficacy trials pertaining to intestinal schistosomiasis and soil-transmitted helminthiasis.
Oliver Bärenbold, G. Raso, J. Coulibaly, E. N'Goran, J. Utzinger, P. Vounatsou   +5 more
semanticscholar   +1 more source