Results 1 to 10 of about 3,265,213 (207)

Environmental characteristics around the household and their association with hookworm infection in rural communities from Bahir Dar, Amhara Region, Ethiopia. [PDF]

PLoS Neglected Tropical Diseases, 2021
Soil-Transmitted Helminths (STH) are highly prevalent Neglected Tropical Disease in Ethiopia, an estimated 26 million are infected. Geographic Information Systems and Remote Sensing (RS) technologies assist data mapping and analysis, and the prediction ...
Melaku Anegagrie, Sofía Lanfri, Aranzazu Amor Aramendia, Carlos Matías Scavuzzo, Zaida Herrador, Agustín Benito, Maria Victoria Periago   +6 more
doaj   +4 more sources

Experimental human hookworm infection: a narrative historical review [PDF]

PLoS Neglected Tropical Diseases, 2021
In 1896, a serendipitous laboratory accident led to the understanding that hookworms propagate infection by penetrating skin, a theory that was then confirmed with the first experimental human infection, reported in 1901.
Paul R. Chapman, Paul Giacomin, Alex Loukas, James S. McCarthy   +3 more
doaj   +5 more sources

Hookworm infection associates with a vaginal Type 1/Type 2 immune signature and increased HPV load [PDF]

Frontiers in Immunology, 2022
Helminth infection-driven changes to immunity in the female reproductive tract (FRT) is an immune axis that is currently understudied but can have major implications for the control of FRT infections.
Millicent A. Omondi, Eya H. Kamassa, Gnatoulma Katawa, Christèle N. Tchopba, Celina Vogelbusch, Marijo Parcina, Edlom P. Tchadié, Oukoe M. Amessoudji, Kathrin Arndts, Simplice D. Karou, Yaovi Ameyapoh, Malewé Kolou, Achim Hoerauf, Achim Hoerauf, Achim Hoerauf, Laura E. Layland, Laura E. Layland, William G. C. Horsnell, William G. C. Horsnell, Manuel Ritter   +19 more
doaj   +3 more sources

Strongyloides stercoralis and hookworm co-infection: spatial distribution and determinants in Preah Vihear Province, Cambodia [PDF]

Parasites & Vectors, 2018
Background Strongyloides stercoralis and hookworm are two soil-transmitted helminths (STH) that are highly prevalent in Cambodia. Strongyloides stercoralis causes long-lasting infections and significant morbidity but is largely neglected, while hookworm ...
Armelle Forrer, Virak Khieu, Fabian Schär, Penelope Vounatsou, Frédérique Chammartin, Hanspeter Marti, Sinuon Muth, Peter Odermatt   +7 more
doaj   +3 more sources

Levels of serum eosinophil cationic protein are associated with hookworm infection and intensity in endemic communities in Ghana. [PDF]

PLoS ONE, 2019
BackgroundThe eosinophil cationic protein (ECP) is a cytotoxic protein mainly secreted by eosinophils granulocytes and plays a role in host defense against parasitic infections.
Benjamin Amoani, Bright Adu, Margaret T Frempong, Tracy Sarkodie-Addo, Samuel Victor Nuvor, Michael D Wilson, Ben Gyan   +6 more
doaj   +3 more sources

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection [PDF]

Frontiers in Immunology, 2018
Soil-transmitted helminths and Mycobacterium tuberculosis frequently coincide geographically and it is hypothesized that gastrointestinal helminth infection may exacerbate tuberculosis (TB) disease by suppression of Th1 and Th17 responses.
Matthew K. O'Shea, Matthew K. O'Shea, Matthew K. O'Shea, Thomas E. Fletcher, Thomas E. Fletcher, Julius Muller, Rachel Tanner, Magali Matsumiya, J. Wendi Bailey, Jayne Jones, Steven G. Smith, Gavin Koh, William G. Horsnell, William G. Horsnell, Nicholas J. Beeching, James Dunbar, James Dunbar, Duncan Wilson, Adam F. Cunningham, Helen McShane   +19 more
doaj   +3 more sources

Micronutrient-Fortified Rice Can Increase Hookworm Infection Risk: A Cluster Randomized Trial.

PLoS ONE, 2016
BackgroundFortification of staple foods is considered an effective and safe strategy to combat micronutrient deficiencies, thereby improving health. While improving micronutrient status might be expected to have positive effects on immunity, some studies
Brechje de Gier, Maiza Campos Ponce, Marlene Perignon, Marion Fiorentino, Kuong Khov, Chhoun Chamnan, Michiel R de Boer, Megan E Parker, Kurt Burja, Marjoleine A Dijkhuizen, Jacques Berger, Katja Polman, Frank T Wieringa   +12 more
doaj   +3 more sources

Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development. [PDF]

Open Forum Infect Dis, 2018
Abstract Background Controlled human hookworm infection (CHHI) is a central component of a proposed hookworm vaccination-challenge model (HVCM) to test the efficacy of candidate vaccines. Critical to CHHI is the manufacture of Necator americanus infective larvae (NaL3) according to current Good ...
Diemert D, Campbell D, Brelsford J, Leasure C, Li G, Peng J, Zumer M, Younes N, Bottazzi ME, Mejia R, Pritchard DI, Hawdon JM, Bethony JM.   +12 more
europepmc   +4 more sources

Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes. [PDF]

Nat Commun, 2023
The reduced prevalence of insulin resistance and type 2 diabetes in countries with endemic parasitic worm infections suggests a protective role for worms against metabolic disorders, however clinical evidence has been non-existent. This 2-year randomised,
Pierce DR, McDonald M, Merone L, Becker L, Thompson F, Lewis C, Ryan RYM, Hii SF, Zendejas-Heredia PA, Traub RJ, Field MA, Rahman T, Croese J, Loukas A, McDermott R, Giacomin PR.   +15 more
europepmc   +2 more sources

Feasibility of controlling hookworm infection through preventive chemotherapy: a simulation study using the individual-based WORMSIM modelling framework [PDF]

Parasites & Vectors, 2015
Background Globally, hookworms infect 440 million people in developing countries. Especially children and women of childbearing age are at risk of developing anaemia as a result of infection. To control hookworm infection and disease (i.e.
Luc E. Coffeng, Roel Bakker, Antonio Montresor, Sake J. de Vlas   +3 more
doaj   +3 more sources