Results 221 to 230 of about 1,478,706 (306)

Glymphatic dysfunction couples with cortical excitation–inhibition imbalance in epilepsy: Evidence from Rasmussen encephalitis

Epilepsia, EarlyView.
Cong Fu et al. demonstrate that glymphatic system dysfunction is linked to enhanced inhibitory cortical activity using diffusion MRI and EEG. These findings highlight a mechanistic link between perivascular fluid dynamics and neuronal activity, suggesting a role for glymphatic function in maintaining cortical stability in epilepsy.
Cong Fu, Yujiao Yang, Pan Gong, Kun Lv, Yilin Liu, Chongyang Tang, Xiongfei Wang, Lixin Cai, Qingzhu Liu, Yuwu Jiang, Taoyun Ji, Guoming Luan   +11 more
wiley   +1 more source

ILAE dietary treatments task force special report: Maternal ketogenic diet exposure in epilepsy pregnancy registries—A call to action

Epilepsia Open, EarlyView.
Abstract Ketogenic dietary therapies (KDTs) are increasingly used worldwide as a non‐pharmacological treatment for epilepsy, including among people of childbearing potential. In many cases, KDTs allow for the reduction of antiseizure medications (ASMs) and lower drug exposure during pregnancy.
Magnhild Kverneland, Valentina De Giorgis, Laura Healy, Kelly Faltersack, Tanya J. W. McDonald, Marisa Armeno, Mackenzie C. Cervenka, Anita Devlin   +7 more
wiley   +1 more source

Climate change effects on biomass and greenhouse gas emissions are ameliorated by nontoxic endophytes in southeastern USA transition zone tall fescue pastures

Grassland Research, EarlyView.
Tall fescue produces more biomass and less carbon dioxide from the soil when it contains its beneficial fungal endophyte. Increased temperatures projected with climate change reduce fescue biomass, while altered rainfall frequency does not. Altering rainfall frequency and increasing temperatures can reduce carbon dioxide emissions from soil.
Rebecca K. McGrail, Jonathan D. Moore, A. Elizabeth Carlisle, Jim A. Nelson, Rebecca L. McCulley   +4 more
wiley   +1 more source

Sex Hormones and Cardiovascular Risk in Type 2 Diabetes: Cohort Study of the Look AHEAD Trial. [PDF]

Diabetes Care
Gisinger T, He JH, Oyeka CP, Ma J, Srialluri N, Woodward M, Michos ED, Kalyani RR, Clark JM, Kautzky-Willer A, Vaidya D, Bennett WL.   +11 more
europepmc   +1 more source

Impact of Smoking on Treatment Outcomes in Patients With Human Papillomavirus‐Related Oropharyngeal Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan, Latifa A. Bazzi, Zequn Sun, Dayton Rand, Asher Park, Shravan Asthana, Alexis Larson, Poonam Yadav, Bharat B. Mittal, Adil Akthar, Sarah Kramer, Jochen H. Lorch, Sandeep Samant, Urjeet Patel, Michelle L. Mierzwa, Leila J. Mady, Katelyn O. Stepan, Laila A. Gharzai   +17 more
wiley   +1 more source

Clinical characteristics and risk factors associated with objective flares in patients with dermatomyositis. [PDF]

Semin Arthritis Rheum
Saygin D, Wang XY, Fitzgerald KC, Albayda J, Paik JJ, Tiniakou E, Adler B, Mammen AL, Christopher-Stine L, Mecoli CA.   +9 more
europepmc   +1 more source

Sex-specific gut mycobiome dysbiosis activates macrophage dectin-1 signaling to drive neurobehavioral deficits in EcoHIV-infected mice. [PDF]

Brain Behav Immun
Li Y, Sakamoto S, Smith MD, Hasegawa Y, Huang M, Li N, Dhaliwal M, Schauermann T, Xiong F, Luo B, Li H, Li Q, Calabresi PA, Volsky D, Slusher BS, Kamiya A, Zhu X.   +16 more
europepmc   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

International Journal of Cancer, EarlyView.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash, Matthew Sperrin, Glen P. Martin, Rashmi Sinha, Charles E. Matthews, Matthias B. Schulze, Anouk Hiensch, Pilar Amiano, Marian L. Neuhouser, Corinne E. Joshu, Elizabeth A. Platz, Heinz Freisling, Marc J. Gunter, Andrew G. Renehan   +13 more
wiley   +1 more source

Impact of Legal Perceptions and Disclosure on Willingness to Undergo HIV Antiretroviral Resistance Testing Among Men Who Have Sex with Men: A Brief Report. [PDF]

AIDS Behav
Neighbors CE, Sanchez T, Jose S, Geller G, Edwards OW, Hannah M, Agostini J, Bollinger J, Henry LM, Sugarman J, Weinfurt K.   +10 more
europepmc   +1 more source

Risk of Head and Neck Cancer in Former Smokers by Subsite: A Multicenter Analysis From the INHANCE Consortium

International Journal of Cancer, EarlyView.
Tobacco use and alcohol consumption are primary risk factors for head and neck squamous cell carcinoma, with combined use occurring in three‐quarters of cases. This large international study of former smokers shows that the risk reduction effect of smoking cessation occurs more slowly for laryngeal cancer than for other head and neck cancer subsites ...
Matheus de Abreu, Luiz Paulo Kowalski, Rossana Mendoza López, Christine Barul, Loredana Radoi, Ettore Bidoli, Jerry Polesel, Victor Wunsch‐Filho, Andrew F. Olshan, Jose Zevallos, Eva Negri, Valeria Edefonti, Beata Świątkowska, Dana Mates, Eleonora Fabianova, Jolanta Lissowska, Oxana Shangina, Paul Brennan, Tamas Pandics, Luigino Dal Maso, Hal Morgenstern, Zuo‐Feng Zhang, Karl Kelsey, Michael McClean, Carlo La Vecchia, Werner Garavello, Chu Chen, Stephen M. Schwartz, Heribert Ramroth, Volker Winkler, Gabriella Cadoni, Stefania Boccia, Hermann Brenner, Gypsyamber D'Souza, Neil Gross, Joshua Muscat, Mahsa Abedini, Michele Sassano, Paolo Boffetta, Mia Hashibe, Yuan‐Chin Amy Lee, Maria Paula Curado   +41 more
wiley   +1 more source