Results 141 to 150 of about 3,898,948 (246)

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

Implementation of new concise care pathways into a software tool to detect and manage comorbidities in older patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS project. [PDF]

Europace
Önder R, Desteghe L, Vandeput E, Lobeek M, Rienstra M, Vijgen J, Heidbuchel H, EHRA-PATHS investigators .   +7 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Development of three-step holistic care pathways to detect and manage comorbidities in patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS consortium. [PDF]

Eur Heart J Open
Önder R, Desteghe L, Vijgen J, Collins R, Dabrowski R, Farkowski MM, de Oliveira Figueiredo MJ, Hereijgers MJM, Hofer D, Lau CP, Lee G, Linz D, Lobeek M, Lopez T, McAuliffe C, Merino JL, Potpara T, Sanders P, Shamloo AS, Sterliński M, Svennberg E, van Deutekom C, Van Gelder I, Rienstra M, Heidbuchel H.   +24 more
europepmc   +1 more source

Structural Transformation to Attain Responsible BIOSciences (STARBIOS2): Protocol for a Horizon 2020 Funded European Multicenter Project to Promote Responsible Research and Innovation. [PDF]

JMIR Res Protoc, 2019
Colizzi V, Mezzana D, Ovseiko PV, Caiati G, Colonnello C, Declich A, Buchan AM, Edmunds L, Buzan E, Zerbini L, Djilianov D, Kalpazidou Schmidt E, Bielawski KP, Elster D, Salvato M, Alcantara LCJ, Minutolo A, Potestà M, Bachiddu E, Milano MJ, Henderson LR, Kiparoglou V, Friesen P, Sheehan M, Moyankova D, Rusanov K, Wium M, Raszczyk I, Konieczny I, Gwizdala JP, Śledzik K, Barendziak T, Birkholz J, Müller N, Warrelmann J, Meyer U, Filser J, Khouri Barreto F, Montesano C.   +38 more
europepmc   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Opportunità dall’Europa: il Programma HORIZON 2020

, 2014
ISFOL, Progetto Cooperazione transnazionale, Opportunità dall’Europa: il Programma HORIZON 2020, Intervento a "Programma Horizon 2020 e il Programma Easi", Roma, Isfol, 5 marzo 2014. Isfol OA: Presentation.
ISFOL, Progetto Cooperazione transnazionale   +1 more
core  

Economic Evaluation of Artificially Intelligent (AI) Diagnostic Systems: Cost Consequence Analysis of Clinician-Friendly Interpretable Computer-Aided Diagnosis (ICADX) Tested in Cardiology, Obstetrics, and Gastroenterology, from the HosmartAI Horizon 2020 Project. [PDF]

Healthcare (Basel)
Chatzikou M, Latsou D, Apostolidis G, Billis A, Charisis V, Rigas ES, Bamidis PD, Hadjileontiadis L.   +7 more
europepmc   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

Advanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka, Zhaolin Liu, Ivan P. Parkin, Guanjie He   +3 more
wiley   +1 more source