Results 41 to 50 of about 87,356,422 (255)

From line to dots: an improved computerised rod and frame system for testing subjective visual vertical and horizontal [PDF]

, 2010
Background Perception of subjective visual vertical (SVV) and horizontal (SVH) has traditionally been measured by rotating a mechanical rod either with or without a frame present. The computerised rod and frame (CRAF) system has previously only been used
Jeff Bagust, Docherty, Sharon, Docherty Sharon, Bagust, Jeffery, Sharon Docherty, Bagust Jeff   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Airborne high spectral resolution lidar observation of pollution aerosol during EUCAARI-LONGREX [PDF]

, 2013
Airborne high spectral resolution lidar observations over Europe during the EUCAARI-LONGREX field experiment in May 2008 are analysed with respect to the optical properties of continental pollution aerosol.
A. Fix, Minikin, Andreas, M. Esselborn, Groß, Silke, Abicht, Florian, Fix, Andreas, A. Minikin, Fix, A., Abicht, F., Esselborn, Michael, S. Groß, F. Abicht, Wirth, M., Minikin, A., Esselborn, M., Groß, S., M. Wirth, Wirth, Martin   +17 more
core   +2 more sources

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Seismic microzonation and soil-structure resonance analysis in Suryabinayak Municipality, Bhaktapur, Nepal: insights from ambient vibration measurements

Geomatics, Natural Hazards & Risk
Bhaktapur, lying in the Kathmandu Basin, suffered damages during the 2015 Gorkha Earthquake, potentially exacerbated by local site effects. This research addresses the lack of site response study on Suryabinayak Municipality, located in the southern part
Dinesh Sakhakarmi, Chandra Kiran Kawan, Amit Prajapati, Chirag Pradhananga, Sudip Karanjit, Subeg Man Bijukchhen   +5 more
doaj   +1 more source

On the Utility of Horizontal-to-Vertical Spectral Ratios of Ambient Noise in Joint Inversion with Rayleigh Wave Dispersion Curves for the Large-N Maupasacq Experiment

Sensors, 2021
Horizontal-to-Vertical Spectral Ratios (HVSR) and Rayleigh group velocity dispersion curves (DC) can be used to estimate the shallow S-wave velocity (VS) structure. Knowing the VS structure is important for geophysical data interpretation either in order
Maik Neukirch, Antonio García-Jerez, Antonio Villaseñor, Francisco Luzón, Jacques Brives, Laurent Stehly   +5 more
doaj   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Antarctic ice sheet thickness estimation using the horizontal-to-vertical spectral ratio method with single-station seismic ambient noise [PDF]

The Cryosphere, 2018
We report on a successful application of the horizontal-to-vertical spectral ratio (H / V) method, generally used to investigate the subsurface velocity structures of the shallow crust, to estimate the Antarctic ice sheet thickness for the first time.
P. Yan, Z. Li, F. Li, F. Li, Y. Yang, W. Hao, F. Bao   +6 more
doaj   +1 more source

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

Annals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti, Anemoon T. Bosch, Job van der Palen, Franciscus S. Leijten, Johannes P. van Dijk, Richard H. C. Lazeron, Roland D. Thijs   +6 more
wiley   +1 more source