Results 91 to 100 of about 1,644,938 (307)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Horizontal mergers and successive oligopoly [PDF]
This paper considers a successive oligopoly setting in which a set of upstream firms sell output non-exclusively to a group of downstream firms using a linear tariff.
Steffen Ziss
core
Kurtosis and skew show longer males in Centrobolus [PDF]
Arthropods, 2020 Sexual Size Dimorphism (SSD) in the diplopod genus Centrobolus has a positive correlation with body size. Length, width and rings are the main components of interspecific variation in diplopod species.
Mark Cooper
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Aging and Cancer, EarlyView.In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
, 2002 The second edition of Horizontal Gene Transfer has been organized to provide a concise and up-to-date coverage of the most important discoveries in this fascinating field. Written by the most prominent gene transfer and genome analytical scientists, this
Kado, Clarence I., Syvanen, Michael.
core
Analysis of Short Time Period of Operation of Horizontal Ground Heat Exchangers
Resources, 2015 Ground source heat pump (GSHP) systems have been proven to have higher efficiency compared to conventional air source heat pump systems for space heating and cooling applications.
Salsuwanda Selamat +2 more
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Classical Horizontal Inequities in the Provision of Agricultural Income Support [PDF]
This paper explores the redistributive effect of classical horizontal inequities induced by agricultural support policy. Within farm type horizontal inequity (HI) is associated with differences in the level of support received by farms of a given type ...
Allanson, Paul
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