Results 191 to 200 of about 499,224 (333)

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Application of the Horizontal Mattress Techniques in Side-to-Side Microvascular Anastomoses Maximizes Intima Eversion, Technique and Clinical Case Report. [PDF]

Neurosurg Pract
Zhao X, Graffeo CS, Bauer AM.
europepmc   +1 more source

HORIZONTAL BRANCH MORPHOLOGY AND MULTIPLE STELLAR POPULATIONS IN THE ANOMALOUS GLOBULAR CLUSTER M 22 [PDF]

, 2013
A. F. Marino, A. P. Milone, K. Lind
openalex   +1 more source

Discovery of Early-Branching Wolbachia Reveals Functional Enrichment on Horizontally Transferred Genes

, 2022
Nicholas Weyandt, Shiva A. Aghdam, Amanda M. V. Brown   +2 more
openalex   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

M²S-YOLOv8: Multi-Scale and Asymmetry-Aware Ship Detection for Marine Environments. [PDF]

Sensors (Basel)
Li P, Qiao D, Mu J, Qi L.
europepmc   +1 more source

Kinematics of the system of blue horizontal branch field stars of the outer Galactic halo [PDF]

, 1994
Jesper Sommer‐Larsen, Chris Flynn, P. R. Christensen   +2 more
openalex   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

DSWFNet: dual-branch fusion of spatial and wavelet features for road extraction from remote sensing images. [PDF]

Sci Rep
Zhang K, As'arry A, Shen X, Hairuddin AA, Hassan MK, Zhu L, Qin W.   +6 more
europepmc   +1 more source

A continuous population of variable stars up to about 1.5 mag above the horizontal branch? [PDF]

, 2007
L. Baldacci
openalex   +1 more source