Results 261 to 270 of about 1,859,132 (364)

Innovating to amplify the voices of young people from marginalized ethnic migrant backgrounds

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract The meaningful participation of young people from marginalized ethnic backgrounds in civic processes is central to the social cohesion of increasingly diverse liberal democracies, but their participation is compromised by a range of barriers resulting in decision‐making that is disconnected from their lives.
Kelsey L. Deane   +7 more
wiley   +1 more source

Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof‐of‐concept study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt   +7 more
wiley   +1 more source

Lecanemab‐Associated Amyloid‐β Protofibril in Cerebrospinal Fluid Correlates with Biomarkers of Neurodegeneration in Alzheimer's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The Clarity AD phase III trial showed that lecanemab reduced amyloid markers in early Alzheimer's disease (AD) and resulted in less decline on measures of cognition and function than placebo. Herein, we aimed to characterize amyloid‐β (Aβ) protofibril (PF) captured by lecanemab in human cerebrospinal fluid (CSF) from living participants with ...
Moeko Noguchi‐Shinohara   +8 more
wiley   +1 more source

Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides

open access: yesAngewandte Chemie, EarlyView.
The hypothesized convergent biosynthesis of triculamin‐like lasso peptides from different biosynthetic gene cluster (BGC) types represented across multiple bacterial phyla. The elucidation of the triculamin non‐canonical BGC and resistance mechanism by heterologous expression in Streptomyces albus and in vitro acetylation with resistance conveying ...
Aske Merrild   +3 more
wiley   +2 more sources

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