Results 241 to 250 of about 5,536,538 (293)

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Erratum: Comparative genomics reveals high prophage diversity and horizontal gene transfer of effectors and phage defence systems in the <i>Pseudomonas syringae</i> complex. [PDF]

Microb Genom
Holtappels D, Rickus GEJ, Morgan T, de Rezende RR, Koskella B, Alfenas-Zerbini P.   +5 more
europepmc   +1 more source

H4K12 Lactylation Impairs Dopaminergic Neuron Energy Metabolism via the HIF‐1α/NDUFS1 Pathway in Parkinson's Disease

Advanced Science, EarlyView.
Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu, Xi Li, Wenxuan He, Fenglin Li, Qican Ou, Yao Liu, Jiang Lei, Yanzi Bao, Huaxin Huang, Wei Feng, Yuanguang Tang, Xiaohui Qiu, Lu Gan, Yuefei Shen, Jin Wang, Yousheng Xiao   +15 more
wiley   +1 more source

Horizontal gene transfer, segregation loss, and the speed of microbial adaptation. [PDF]

Evol Lett
McLeod DV, Gandon S.
europepmc   +1 more source

Comparative genomics reveals high prophage diversity and horizontal gene transfer of effectors and phage defence systems in the <i>Pseudomonas syringae</i> complex. [PDF]

Microb Genom
Holtappels D, Rickus GEJ, Morgan T, de Rezende RR, Koskella B, Alfenas-Zerbini P.   +5 more
europepmc   +1 more source

Evidence for Transcription and Horizontal Gene Transfer in Dipteran Germline-Restricted Chromosomes

Kyriacou RG, Herbette M, Baird RB, Monteith KM, Ross L, Hodson CN.   +5 more
europepmc   +1 more source

Horizontal gene transfer of the Pytheas sequence from Cuscuta to Orobanche via a host-mediated pathway. [PDF]

Sci Rep
Denysenko-Bennett M, Kwolek D, Góralski G, Szklarczyk M, Piwowarczyk R, Stefanović S, Schneider AC, Joachimiak AJ.   +7 more
europepmc   +1 more source

Mechanisms, detection, and impact of horizontal gene transfer in plant functional evolution. [PDF]

Plant Cell
Mariault L, Puginier C, Keller J, El Baidouri M, Delaux PM.   +4 more
europepmc   +1 more source

Gut Microbe-Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation. [PDF]

Adv Sci (Weinh)
HuangFu N, Zhu X, Tang Z, Wang L, Zhang K, Li D, Ji J, Cui J, Guo Z, Luo J, Gao X.   +10 more
europepmc   +1 more source

Correction to 'Current state and future prospects of Horizontal Gene Transfer detection'. [PDF]

NAR Genom Bioinform
europepmc   +1 more source