Results 281 to 290 of about 384,646 (364)

Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides

open access: yesAngewandte Chemie, EarlyView.
The hypothesized convergent biosynthesis of triculamin‐like lasso peptides from different biosynthetic gene cluster (BGC) types represented across multiple bacterial phyla. The elucidation of the triculamin non‐canonical BGC and resistance mechanism by heterologous expression in Streptomyces albus and in vitro acetylation with resistance conveying ...
Aske Merrild   +3 more
wiley   +2 more sources

Green‐to‐red spectral labeling: A novel polysynaptic retrograde tracing strategy in the marker footprint mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To compensate for the fluorescence loss in rabies virus–derived neuronal tracing tools caused by non‐cytolytic immune clearance (NCLIC) in retrograde tracing, we developed a novel green‐to‐red spectral labeling (GTR) strategy based on the NCLIC phenomenon and developed a novel marker footprints mouse to support the strategy.
Yige Song   +4 more
wiley   +1 more source

Pangenome Analysis of the Plant Pathogen Pseudomonas syringae Reveals Unique Natural Products for Niche Adaptation

open access: yesAngewandte Chemie, EarlyView.
A pangenome analysis of the plant pathogen Pseudomonas syringae reveals two novel natural product families that facilitate niche adaptation. Comprehensive genomic and chemical analyses uncover unique biosynthetic gene clusters linked to host specificity and environmental fitness.
Shuaibing Zhang   +7 more
wiley   +2 more sources

A natural mechanism of eukaryotic horizontal gene transfer

open access: yes
Urquhart AS   +3 more
europepmc   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He   +11 more
wiley   +1 more source

Unraveling the Complexity of Divalent Hydride Electrolytes in Solid‐State Batteries via a Data‐Driven Framework with Large Language Model

open access: yesAngewandte Chemie, EarlyView.
We present a data‐driven framework that combines experimental and computational information to accelerate the discovery of high‐performance divalent hydride solid‐state electrolytes, enabling precise predictions of activation energies and novel ionic migration mechanisms which are essential for next‐generation energy storage technology.
Qian Wang   +11 more
wiley   +2 more sources

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