Results 51 to 60 of about 2,318,055 (330)

Pressure gradient prediction of gas-liquid two-phase pipe flow in horizontal gas wells

Shenzhen Daxue xuebao. Ligong ban, 2022
Accurate prediction of pressure gradient in gas wells is the theoretical basis for dynamic analysis, optimization of production and deliquification technologies design.
LUO Chengcheng, WU Ning, WANG Hua, LIU Yonghui, ZHANG Teng, WANG Benqiang, WU Pengbo, LIU Jun   +7 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

On Single Well Forced Gradient Tracer Tests: Implications of Aquifer Physical Heterogeneity and Tracer Behaviour [PDF]

, 2010
Single well forced gradient tracer tests are a potential cost-effective approach to estimate in situ aquifer contaminant fate and transport parameters for use in natural attenuation assessments and remediation schemes.
Barns, Gareth L
core  

Permeability characteristics of silty sand under vertical and horizontal seepages

Yantu gongcheng xuebao, 2020
The influence of seepage direction on the silt permeability are studied. The vertical and horizontal seepage tests of silty sand are carried out by using the self-designed devices.
ZHANG Can-hong 1, 3, QIAN Ya-jun 2, ZHONG Qi-ming 2, WANG Bao-tian 3
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Forecast of fractured horizontal well productivity in dual permeability layers in volcanic gas reservoirs

Petroleum Exploration and Development, 2014
In view of the flow particularity of fractured horizontal wells in dual permeability layers in volcanic gas reservoirs, based on the equivalent flowing resistance method and superposition principle, a new productivity forecasting method for fractured ...
Zhiping WANG, Bo RAN, Min TONG, Chunming WANG, Qingfeng YUE   +4 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Precise acoustic seafloor positioning with joint estimation of sound speed field structure using a layered sound speed gradient model

Satellite Navigation
The accuracy of GNSS-Acoustic (GNSS-A) seafloor positioning is much affected by spatiotemporal variability in the ocean Sound Speed Field (SSF). The conventional depth-invariant horizontal sound speed gradient models represent the water-column sound ...
Wenlong Yang, Tianhe Xu, Junting Wang, Yangfan Liu, Zhen Xiao   +4 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source