Results 51 to 60 of about 1,420,872 (289)

Permeability characteristics of silty sand under vertical and horizontal seepages

open access: yesYantu gongcheng xuebao, 2020
The influence of seepage direction on the silt permeability are studied. The vertical and horizontal seepage tests of silty sand are carried out by using the self-designed devices.
ZHANG Can-hong 1, 3, QIAN Ya-jun 2, ZHONG Qi-ming 2, WANG Bao-tian 3
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Forecast of fractured horizontal well productivity in dual permeability layers in volcanic gas reservoirs

open access: yesPetroleum Exploration and Development, 2014
In view of the flow particularity of fractured horizontal wells in dual permeability layers in volcanic gas reservoirs, based on the equivalent flowing resistance method and superposition principle, a new productivity forecasting method for fractured ...
Zhiping WANG   +4 more
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Precise acoustic seafloor positioning with joint estimation of sound speed field structure using a layered sound speed gradient model

open access: yesSatellite Navigation
The accuracy of GNSS-Acoustic (GNSS-A) seafloor positioning is much affected by spatiotemporal variability in the ocean Sound Speed Field (SSF). The conventional depth-invariant horizontal sound speed gradient models represent the water-column sound ...
Wenlong Yang   +4 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

HORIZONTAL MERGERS FOR BUYER POWER [PDF]

open access: yes
Salant et al. (1983) showed in a Cournot setting that horizontal mergers are unprofitable because outsiders react by increasing their output. We show that this negative effect may be compensated by the positive effect that horizontal mergers have on the ...
Lluís Bru Martínez   +1 more
core   +2 more sources

Fluid pressure gradient characteristics and petroleum geological significance in Shahejie Formation of Bonan Sag in Jiyang Depression

open access: yesShiyou shiyan dizhi
Fluid pressure gradient is the rate at which residual fluid pressure changes both spatially and temporally. It serves as an important parameter for indicating oil and gas migration pathways and accumulation zones, holding great geological significance ...
Peng LIU   +4 more
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

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