Results 41 to 50 of about 144,820 (261)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Lithfacies and “sweet spot” interval of marine shale in southern Sichuan: A case study of Shuanghe Outcrop in Wufeng-Longmaxi Formation, Changning

Youqicang pingjia yu kaifa, 2022
With the comprehensive application of the photography of full thin section, the optical microscope observation of small thin sections, TOC test, whole rocks X-ray composition test, physical property analysis and the observation of field emission scanning
WANG Hongyan, DONG Dazhong, SHI Zhensheng, QIU Zhen, LU Bin, SHAO Nan, SUN Shasha, ZHANG Surong   +7 more
doaj  

Millimeter-wave multi-mode circular antenna array for uni-cast multi-cast and OAM communication

Scientific Reports, 2021
This paper investigates uni-/multi-cast and orbital angular momentum (OAM) mode data transmission in orthogonal directions by the utilization of a new circular antenna array, operating at 28 GHz.
Stylianos D. Assimonis, Muhammad Ali Babar Abbasi, Vincent Fusco   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Study on Field Test and Seismic Performance of MJS Joint Microdisturbance Reinforcement on Existing Tunnel

Shock and Vibration, 2021
Metro Jet System (MJS) joint microdisturbance reinforcement is often adopted to strengthen and remediate existing tunnels that are severely deformed by under-construction peripheral works, but analysis related to the reinforcement system of tunnel under ...
Zhanyou Luo, Yongheng Deng, Baoping Zou, Jianfeng Zhu, Mingyao Jiang, Kuangqin Xie   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Big data paradox and modeling strategies in geological modeling based on horizontal wells data

Petroleum Exploration and Development, 2017
Based on analysis of horizontal well data characteristics, the differences of data distribution and variogram between vertical and horizontal wells in MPE3 oil field of Orinoco heavy oil belt were compared, and modeling strategies were proposed to cope ...
Wensong HUANG, Jiahua WANG, Heping CHEN, Fang XU, Zheng MENG, Yonghao LI   +5 more
doaj   +1 more source

A Geometrical Account to Explain the Fat-Face Illusion

i-Perception, 2020
Investigations of the “fat-face” illusion have unanimously agreed that the illusion is face-specific. Here, we offer several manipulations to highlight that the fat-face illusion is not restricted to the bottom image, isn’t a property of internal ...
Amit Rawal, Philip Tseng
doaj   +1 more source