Results 191 to 200 of about 575,551 (307)
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Effects of cinnamon supplementation combined with exercise training on anthropometric indices and reproductive hormones in overweight and obese women. [PDF]
Ahmadi F, Khaleghi MM, Zar A.
europepmc +1 more source
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source
Association Between Leukocytospermia and Varicocele in Patients With Infertility. [PDF]
Eldamnhoury EM, El-Sakka AI.
europepmc +1 more source
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang +17 more
wiley +1 more source
Puberty-Associated Gingival Enlargement Exacerbated by Polycystic Ovary Syndrome: A Case Report. [PDF]
Dhalla N +5 more
europepmc +1 more source
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Circulating sex hormones, specifically estrogen in females and testosterone in males, are associated with ambient environmental temperature during prolonged physical training. [PDF]
Giersch GEW +8 more
europepmc +1 more source

