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Neoplasia: An International Journal for Oncology Research, 1999 The calcium-sensing receptor (CaR) is a G-proteincoupled receptor that is widely expressed, has tissuespecific functions, regulates cell growth. Activating mutations of this receptor cause autosomal dominant hypocalcemia, a syndrome characterized by ...
Ana O. Hoff +5 more
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Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis
Frontiers in Endocrinology, 2023 Age-related cerebrovascular pathologies, ranging from cerebromicrovascular functional and structural alterations to large vessel atherosclerosis, promote the genesis of vascular cognitive impairment and dementia (VCID) and exacerbate Alzheimer’s disease.
Marisa A. Bickel +12 more
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Luteinizing hormone-releasing hormone antagonists [PDF]
Expert Opinion on Therapeutic Patents, 2009 Luteinizing hormone-releasing hormone (LH-RH) plays a central role in the vertebrate reproduction by regulating gonadal activity. Based on its binding to pituitary LH-RH receptors, as well as to LH-RH receptors expressed on cancer cells, LH-RH agonists and antagonists have been developed for different therapeutic applications.Here we give an overview ...
Mezö, Gábor, Manea, Marilena
openaire +3 more sources
Evidence of the indirect hormonal activity of prohormones using liver S9 metabolic bioactivation and an androgen bioassay [PDF]
, 2008 Prohormones such as dehydroepiandrosterone (DHEA) are steroid precursors that do not show hormonal activity by themselves. Abuse of these prohormones in cattle fattening is hard to prove because of strong in vivo metabolism and the difficulty to detect ...
Bovee, T.F.H. +4 more
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Acta Obstetricia et Gynecologica Scandinavica, 2022 Introduction In this open‐label, randomized controlled, non‐inferiority, multicenter study we aimed to study the risk of termination of pregnancy within 1 year postpartum, the safety profile and patient acceptability after early postpartum insertion of a
Karin Lichtenstein Liljeblad +2 more
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Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]
, 2017 Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
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Study of Sexual Dysfunction among Females with Combined Oral Contraception [COC] versus Intrauterine Hormonal Device [PDF]
International Journal of Medical Arts, 2020 Background: Sexuality in females is a multidimensional issue of psychological, physiological and cultural components. Evaluation of sexual partner, intimate relationships, and past abusive relationships or sexual trauma is crucial in female sexual ...
Alaa Talaat +2 more
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Portal Venous Thrombosis Associated with Use of Etonogestrel/ethinyl Estradiol Vaginal Ring [PDF]
, 2020 Introduction: Portal venous thrombosis is a life-threatening cause of abdominal pain. In younger patients, heritable thrombophilias, pregnancy, tobacco use, and oral contraceptives are associated.Case Report: A 26-year-old woman prescribed contraceptive ...
Bailey, Katelynn E. +1 more
core
Hormonal therapy for cancer [PDF]
, 2016 Hormone therapy is an effective and non-toxic therapy for oestrogen and progesterone receptor-positive breast cancer and prostate cancer. Serum levels of oestradiol and testosterone are controlled by the hypothalamic–pituitary–gonadal pathway. Oestradiol
Abraham, Jacinta +1 more
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The effect of combined preconditioning strategies on isokinetic strength in well trained kickboxers
Physical Education of Students, 2018 Background & Study Aim: The use of preconditioning strategies (PconSt) alone has a positive impact on performance. However, it is thought that there will be more impact on the performance of the combined preconditioning strategies, and this is the first ...
A. Yilmaz, V.V. Gurses, M. Gulsen
doaj +1 more source