Results 81 to 90 of about 575,551 (307)

Hormonal contraception use during relationship formation and sexual desire during pregnancy [PDF]

open access: yes, 2015
Women who are regularly cycling exhibit different partner preferences than those who use hormonal contraception. Preliminary evidence appears to suggest that during pregnancy women’s partner preferences also diverge from those prevalent while ...
Jan Havlíček   +7 more
core   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Evaluation of oral health during pregnancy and implementation of maternal oral screening tool and referral process in pregnant women: A cross-sectional study

open access: yesJournal of Family Medicine and Primary Care
Background: A pregnant woman undergoes significant changes in the hormonal levels within her body that can be reflected both systematically as gestational diabetes and as intraoral conditions like gingivitis, dental caries, or pregnancy epulis.
Ankit Mahajan   +5 more
doaj   +1 more source

Breast cancer and hormonal contraceptives : collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies

open access: yes, 1996
The use of female sex hormones as contraceptives began in 1960, since when an estimated 200 million women throughout the world have used them.1 The most widely used type of hormonal contraceptive has been the combined oral contraceptive, which contains ...
Collaborative Group on Hormonal Factors in Breast Cancer
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Self-reported dominance in women: Associations with hormonal contraceptive use, relationship status, and testosterone [PDF]

open access: yes, 2015
How to achieve dominance in a group is a recurrent challenge for individuals of many species, including humans. Previous research indicates that both relationship status and contraceptive use appear to moderate women’s testosterone levels.
Roberts, S Craig   +3 more
core   +1 more source

Menstrual cycle characteristics, hormonal contraception vs no hormonal contraception.

open access: yes, 2023
Menstrual cycle characteristics, hormonal contraception vs no hormonal contraception.
Jan Y. Verbakel (9088610)   +8 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer

open access: yes, 1997
Background The Collaborative Group on Hormonal Factors in Breast Cancer has brought together and reanalysed about 90% of the worldwide epidemiological evidence on the relation between risk of breast cancer and use of hormone replacement therapy (HRT).
D. Bull   +5 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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