Results 11 to 20 of about 1,024,738 (75)

Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.

open access: yesNew England Journal of Medicine, 2001
BACKGROUND Once-daily injections of parathyroid hormone or its amino-terminal fragments increase bone formation and bone mass without causing hypercalcemia, but their effects on fractures are unknown.
R. Neer   +11 more
semanticscholar   +1 more source

The steroid and thyroid hormone receptor superfamily.

open access: yesScience, 1988
Analyses of steroid receptors are important for understanding molecular details of transcriptional control, as well as providing insight as to how an individual transacting factor contributes to cell identity and function.
R. M. Evans
semanticscholar   +1 more source

THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.

open access: yesBiochemical Journal, 1963
A simple and rapid method is presented for the preparation of I/sup 131/- labeled human growth hormone of high specific radioactivity (240-300 mu C/ mu g). Low amounts of carrierfree I/sup 131/ iodide (2 mC) are allowed to react, without prior treatment,
F. Greenwood, W. Hunter, J. Glover
semanticscholar   +1 more source

Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer.

open access: yesNew England Journal of Medicine, 2015
BACKGROUND Androgen-deprivation therapy (ADT) has been the backbone of treatment for metastatic prostate cancer since the 1940s. We assessed whether concomitant treatment with ADT plus docetaxel would result in longer overall survival than that with ADT ...
C. Sweeney   +16 more
semanticscholar   +1 more source

Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.

open access: yesNew England Journal of Medicine, 2012
BACKGROUND Resistance to endocrine therapy in breast cancer is associated with activation of the mammalian target of rapamycin (mTOR) intracellular signaling pathway.
J. Baselga   +20 more
semanticscholar   +1 more source

Plant hormone-mediated regulation of stress responses

open access: yesBMC Plant Biology, 2016
Being sessile organisms, plants are often exposed to a wide array of abiotic and biotic stresses. Abiotic stress conditions include drought, heat, cold and salinity, whereas biotic stress arises mainly from bacteria, fungi, viruses, nematodes and insects.
Vivek Verma   +2 more
semanticscholar   +1 more source

Multiple levels of crosstalk in hormone networks regulating plant defense

open access: yesThe Plant Journal, 2020
Summary Plant hormones are essential for regulating the interactions between plants and their complex biotic and abiotic environments. Each hormone initiates a specific molecular pathway and these different hormone pathways are integrated in a complex ...
N. Aerts   +2 more
semanticscholar   +1 more source

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.

open access: yesJournal of Clinical Investigation, 2004
Hypoferremia is a common response to systemic infections or generalized inflammatory disorders. In mouse models, the development of hypoferremia during inflammation requires hepcidin, an iron regulatory peptide hormone produced in the liver, but the ...
E. Nemeth   +6 more
semanticscholar   +1 more source

AP2/ERF Transcription Factor Regulatory Networks in Hormone and Abiotic Stress Responses in Arabidopsis

open access: yesFrontiers in Plant Science, 2019
Dynamic environmental changes such as extreme temperature, water scarcity and high salinity affect plant growth, survival, and reproduction. Plants have evolved sophisticated regulatory mechanisms to adapt to these unfavorable conditions, many of which ...
Zhouli Xie   +3 more
semanticscholar   +1 more source

The Crosstalks Between Jasmonic Acid and Other Plant Hormone Signaling Highlight the Involvement of Jasmonic Acid as a Core Component in Plant Response to Biotic and Abiotic Stresses

open access: yesFrontiers in Plant Science, 2019
Plant hormones play central roles in plant growth, developmental processes, and plant response to biotic and abiotic stresses. On the one hand, plant hormones may allocate limited resources to the most serious stresses; on the other hand, the crosstalks ...
Jing Yang   +6 more
semanticscholar   +1 more source

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