Results 11 to 20 of about 1,323,336 (317)

The neutral amino acid transporter SLC7A10 in adipose tissue, obesity and insulin resistance

Frontiers in Cell and Developmental Biology, 2022
Obesity, insulin resistance and type 2 diabetes represent major global health challenges, and a better mechanistic understanding of the altered metabolism in these conditions may give improved treatment strategies. SLC7A10, a member of the SLC7 subfamily
Regine Åsen Jersin, Regine Åsen Jersin, Laura Roxana Jonassen, Laura Roxana Jonassen, Simon Nitter Dankel, Simon Nitter Dankel   +5 more
doaj   +1 more source

Bilateral Carotid Body Paraganglioma

Acta Médica Portuguesa, 2021
N/a.
Wasita Warachit, Natnicha Houngngam, Thiti Snabboon   +2 more
doaj   +1 more source

In the Model Cell Lines of Moderately and Poorly Differentiated Endometrial Carcinoma, Estrogens Can Be Formed via the Sulfatase Pathway

Frontiers in Molecular Biosciences, 2021
Endometrial cancer (EC) is the most common gynecological malignancy in resource-abundant countries. The majority of EC cases are estrogen dependent but the mechanisms of estrogen biosynthesis and oxidative metabolism and estrogen action are not ...
Renata Pavlič, Marija Gjorgoska, Eva Hafner, Maša Sinreih, Kristina Gajser, Stefan Poschner, Walter Jäger, Tea Lanišnik Rižner   +7 more
doaj   +1 more source

Ligand-independent androgen receptors promote ovarian teratocarcinoma cell growth by stimulating self-renewal of cancer stem/progenitor cells

Stem Cell Research, 2014
Background: Ovarian teratocarcinoma (OVTC) arises from germ cells and contains a high percentage of cancer stem/progenitor cells (CSPCs), which promote cancer development through their ability to self-renew.
Wei-Min Chung, Wei-Chun Chang, Lumin Chen, Tze-Yi Lin, Liang-Chi Chen, Yao-Ching Hung, Wen-Lung Ma   +6 more
doaj   +1 more source

Long non-coding RNAs potentially function synergistically in the cellular reprogramming of SCNT embryos

BMC Genomics, 2018
Background Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modification disorders.
Fengrui Wu, Yong Liu, Qingqing Wu, Dengkun Li, Ling Zhang, Xiaoqing Wu, Rong Wang, Di Zhang, Shaorong Gao, Wenyong Li   +9 more
doaj   +1 more source

Luteinizing hormone-releasing hormone antagonists [PDF]

Expert Opinion on Therapeutic Patents, 2009
Luteinizing hormone-releasing hormone (LH-RH) plays a central role in the vertebrate reproduction by regulating gonadal activity. Based on its binding to pituitary LH-RH receptors, as well as to LH-RH receptors expressed on cancer cells, LH-RH agonists and antagonists have been developed for different therapeutic applications.Here we give an overview ...
Mezö, Gábor, Manea, Marilena
openaire   +3 more sources

Omics for understanding the tolerant mechanism of Trichoderma asperellum TJ01 to organophosphorus pesticide dichlorvos

BMC Genomics, 2018
Backgroud Though it is toxic to humans, dichlorvos is a widely used chemical pesticide and plays an important role in the control of plant pests. The application of a combination of the biocontrol agent Trichoderma with dichlorvos may reduce the need for
Qiong Wu, Mi Ni, Guisheng Wang, Qianqian Liu, Meixia Yu, Jun Tang   +5 more
doaj   +1 more source

On the role of dauer in the adaptation of nematodes to a parasitic lifestyle

Parasites & Vectors, 2021
Nematodes are presumably the most abundant Metazoa on Earth, and can even be found in some of the most hostile environments of our planet. Various types of hypobiosis evolved to adapt their life cycles to such harsh environmental conditions.
Lieke E. Vlaar, Andre Bertran, Mehran Rahimi, Lemeng Dong, Jan E. Kammenga, Johannes Helder, Aska Goverse, Harro J. Bouwmeester   +7 more
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Bisphenol A interferes with lncRNA Fhadlos2 and RUNX3 association in adolescent mouse ovary

Ecotoxicology and Environmental Safety, 2023
Bisphenol A (BPA) has a number of adverse effects on the reproductive development of females. In particular, the mechanism of disruption of ovarian development in adolescent mice is still unclear.
Yilei Zhang, Xin Xie, Huimin Cheng, Yadi Zhang, Haili Li, Yan Zhu, Rong Wang, Wenyong Li, Ruitao Wang, Fengrui Wu   +9 more
doaj   +1 more source

The role of strigolactones in P deficiency induced transcriptional changes in tomato roots

BMC Plant Biology, 2021
Background Phosphorus (P) is an essential macronutrient for plant growth and development. Upon P shortage, plant responds with massive reprogramming of transcription, the Phosphate Starvation Response (PSR). In parallel, the production of strigolactones (
Yanting Wang, Hernando G. Suárez Duran, Jan C. van Haarst, Elio G.W.M Schijlen, Carolien Ruyter-Spira, Marnix H. Medema, Lemeng Dong, Harro J. Bouwmeester   +7 more
doaj   +1 more source